摘要
目的观察布地奈德联合盐酸氨溴索雾化吸入治疗小儿支气管肺炎的疗效。方法 2011年7-12月医院儿科就诊的小儿支气管肺炎患儿156例,随机分为A组和B组,两组患儿均接受常规基础综合治疗,在此基础上A组患儿接受雾化吸入盐酸氨溴索,B组患儿在接受雾化吸入盐酸氨溴索和布地奈德联合治疗,疗程均为7d;比较治疗后两组患儿支气管肺炎各临床症状及持续时间。结果治疗后B组发热、咳嗽、气喘、啰音和肺部X线阴影症状发生率分别为7.69%、11.54%、6.41%、14.10%和16.67%,均较治疗前显著降低(P<0.01),并且上述症状发生率均显著低于A组患儿;治疗后B组患儿的发热、咳嗽、气喘、肺部啰音、X线阴影持续时间分别为(2.21±0.59)d、(4.52±0.42)d、(3.98±0.58)d、(5.87±0.50)d、(6.24±0.57)d,均显著短于A组(P<0.01)。结论布地奈德联合盐酸氨溴索治疗小儿支气管肺炎疗效显著,值得临床推荐。
OBJECTIVE To observe the efficacy of ambroxol hydrochloride combined with budesonide by aerosol inhalation in the treatment of the children with bronchial pneumonia. METHODS A total of 156 children with bronchial pneumonia, who enrolled the pediatrics department from Jul 2011 to Dec 2011, were randomly divided into Group A and Group B. The children in the group A received ambroxol hydrochloride by aerosol inhalation besides the general basic treatment, and the children in the group B received ambroxol hydrochloride plus budesonide by aerosol inhalation general besides basic treatment. Both of the treatment courses were 7 days; the clinical symptoms of the bronchial pneumonia as well as their durations were compared after the treatment. RESULTS In the group B the incidence rates of fever, cough, asthma, rhonchus and shadows of X ray in lung after treatment were 7.69 %, 11.54 %, 6.41 %, 14.10 % , and 16.67 %, respectively, which were significantly decreased as compared with those before the treatment （P〈0.01）, and the incidence rates of the symptoms mentioned above were significantly lower in the group B than in the group A; in the group B the duration of fever, cough, asthma, rhonchus and shadows of X-ray in lung after the treatment were respectively （2.21 ± 0.59） days, （4.52 4±0.42） days, （3.98±0.58） days, （5.87±0.50） days,and （6.24±0.57） days, which were significantly shorter than those in the group A （P〈0.01）. CONCLUSION Ambroxol hydrochloride combined budesonide by aerosol inhalation is effective to treat the children with bronchial pneumonia,thus worthy of being recommended in the hospital.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2013年第1期100-102,共3页
Chinese Journal of Nosocomiology
关键词
小儿支气管肺炎
布地奈德
氨溴索
疗效
Pediatric bronchial pneumonia
Budesonide
Ambroxol hydrochioride
Efficacy
