摘要
[目的]探讨肺栓塞患者纤维蛋白原与D-二聚体测定的临床价值。[方法]对96例经临床确诊为肺栓塞患者的纤维蛋白原、D-二聚体进行检测并与健康对照组比较。[结果]肺栓塞组纤维蛋白原、D-二聚体水平与对照组比较,差异有显著意义(P<0.01)。纤维蛋白原单独检测的灵敏度和特异性分别为68.8%和35.4%;D-二聚体单独检测的灵敏度和特异性分别为91.7%和43.8%;两者联合检测的灵敏度和特异性分别为95.8%和57.3%。[结论]血浆纤维蛋白原和D-二聚体联合测定可作为肺栓塞诊断的首选试验,可在临床可疑肺栓塞的患者中推广应用。
Obstract： [ Objective ] To investigate the clinical value of testing fibrinogen and D-dimer in patients with pulmonary embolism. [ Methods ] Fibrinogen and D-dimer of 96 patients with pulmonary embolism were tested, and they were compared with those in the healthy control group. [ Results ] Level of fibrinogen and D-dimer in pulmonary embolism group and control group showed great dif- ferences （P 〈0.01）. Sensitivity and specificity of fibrinogen detection alone were 68,8% and 35.4% respectively; those of D-dimer were 91.7% and 43.8% respectively, while sensitivity and specificity of combined testing were respectively 95.8% and 57.3%. [Con- clusion ] Combined testing of plasma fibrinogen and D-dimer is considered to be the preferred test for diagnosis of pulmonary em- bolism, so it could be applied in suspected cases.
出处
《广西中医药大学学报》
2012年第4期1-2,共2页
Journal of Guangxi University Of Chinese Medicine
