摘要
通过查阅近几年国内外有关中药口服渗透泵制剂相关的文献,发现在中药单一成分、有效部位和复方等方面均有研究报道,内容主要是渗透泵制剂的制备工艺和体外释放度评价,也有制剂缓释作用综合评价方法和体外释放机制的探索,综述了近年来中药口服渗透泵制剂的研究进展。随着中医药基础研究的深入,渗透泵制剂技术的发展,中药口服渗透泵制剂研究有着广阔的发展前景。
This paper searched relevant literatures with oral osmotic pump preparation, the results showed that the studies on the monomer compounds, effective fractions, and compound prescriptions of Chinese materia medica （CMM） have been reported. The reports are mainly focused on the preparation technology, evaluation on in vitro release, the comprehensive evaluation method of sustained-release preparation, and the mechanism of in vitro release. The research progress in oral osmotic pump preparations of CMM in recent years is reviewed. With the further development of basic research of traditional Chinese medicines and preparation technology of osmotic pumps, the studies on the oral osmotic pump preparations of CMM will have the broad developing prospects.
出处
《现代药物与临床》
CAS
2012年第6期642-646,共5页
Drugs & Clinic
关键词
中药
渗透泵
控释制剂
零级释放
制备工艺
Chinese materia medica （CMM）
osmotic pumps
sustained-release preparation
preparation technology
