摘要
1α-25羟基维生素D3(骨化三醇)是一种重要的甾体激素,临床上广泛用于治疗各类自身性免疫疾病以及癌症。本文介绍了1α-25-二羟基维生素D3的全合成与半合成方案并且对这些合成方法的优劣作了初步的评价,并展望了今后合成的发展方向。
1α,25-dihydroxy-vitamin D3 was widely used as a hormone for curing autoimmune disease; autoimmune disorders (AID) and cancer in clinic. The characters and synthesis of 1α,25-dihydroxy-vitamin D3 and the tendency for synthesis of this medicine were briefly introduced.
出处
《浙江化工》
CAS
2012年第11期22-25,共4页
Zhejiang Chemical Industry