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1α-25-二羟基维生素D_3合成方法综述 被引量:1

A Review of the Synthesis of 1α,25-Dihydroxy-Vitamin D_3
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摘要 1α-25羟基维生素D3(骨化三醇)是一种重要的甾体激素,临床上广泛用于治疗各类自身性免疫疾病以及癌症。本文介绍了1α-25-二羟基维生素D3的全合成与半合成方案并且对这些合成方法的优劣作了初步的评价,并展望了今后合成的发展方向。 1α,25-dihydroxy-vitamin D3 was widely used as a hormone for curing autoimmune disease; autoimmune disorders (AID) and cancer in clinic. The characters and synthesis of 1α,25-dihydroxy-vitamin D3 and the tendency for synthesis of this medicine were briefly introduced.
作者 许文灏 金灿
出处 《浙江化工》 CAS 2012年第11期22-25,共4页 Zhejiang Chemical Industry
关键词 1α-25-二羟基维生素D3 25-羟基-7-去氢胆固醇 合成方法 1α,25-dihydroxy-vitamin D3 cholesta-5,7-diene-3,25-dio1 synthesis
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