期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

肺上皮样血管内皮瘤的影像学表现 被引量：2

Imaging findings of pulmonary epithelioid hemangioendothelioma
在线阅读 下载PDF
导出
摘要 目的探讨肺上皮样血管内皮瘤(PEH)的影像学表现。方法回顾性分析5例病理证实的PEH患者的影像学(多层螺旋CT和PET-CT)资料。结果所有5例PET患者均为女性,年龄29～56岁。多层螺旋CT均表现为双肺多发结节,边界可清楚或模糊,沿支气管血管束分布,部分结节内有钙化,部分结节周边见磨玻璃密度影(GGO)。3例行PET-CT检查,表现为无或者轻度FDG摄取。3例同时合并肝脏受累,2例合并骨骼受累。4例行免疫组化检查,均有CD34和FⅧ阳性表达、3例CD31阳性表达。结论 PEH是一种少见的肺血管源性肿瘤,多层螺旋CT和PET-CT对PEH的诊断和病程评估具有一定意义,最终确诊有赖于组织病理学及免疫组化检查。 Objective To describe and illustrate the radiological findings of pulmonary epithelioid hemangioendothe- lioma （PEH）. Methods Multi-slice spiral CT and PET-CT findings of 5 PEH patients confirmed by pathology were ana- lyzed retrospectively. Results All 5 patients were females pulmonary nodules in MSCT, with perivascular distribution whose age ranges from 29 to 56, were presented as multiple Some nodules were of calcification inside and some were ob- served with ground-glass opacity （GGO）. Of the PET-CT in 3 patients, pulmonary nodules showed none or mild18 F-FDG up- take. Hepatic lesions occurred in 3 patients and bone lesions in 2 patients simultaneously. Immunohistochemieal analysis con- ducted in 4 patients showed CD34 expression, factor wm expressed in all and CD31 expressed in 3 patients. Conclusion PEH is a rare vascular tumor of the lung commonly among young women. MSCT and PET-CT both provide valuable informa- tion for diagnosis and clinical evaluation, yet the definite diagnosis relies on pathological and immunohistoehemical study.
作者 李蒙 吴宁 刘瑛
机构地区 中国医学科学院、北京协和医学院、肿瘤医院影像诊断科 中国医学科学院、北京协和医学院、肿瘤医院PET-CT中心
出处 《癌症进展》 2012年第5期450-456,共7页 Oncology Progress
关键词 肺肿瘤 上皮样 血管内皮瘤 多层螺旋CT PET—CT 免疫组化 lung neoplasms epithelioid hemangioendothelioma multislice spiral computed tomography posi- tron-emission tomography and computed tomography immunohistoehemistry
分类号 R734.2 [医药卫生—肿瘤] R730.44 [医药卫生—肿瘤]
  • 相关文献

参考文献24

  • 1Leleu O, Lenglet F, Clarot C, et al. Pulmonary epithelioid haemangioendothelioma : reports of three cases and a review of the literature [J]. Rev Mal Respir, 2010, 27 (7): 778 - 783.
  • 2Dail DH, Liebow AA, Gmelich JT, et al. Intravascular, bronchiolar, and alveolar tumor of the lung (IVBAT). An analysis of twenty cases of a peculiar sclerosing endothelial tumor [J]. Cancer, 1983, 51 (3):452-464.
  • 3Corrin B, Manners B, Millard M, et al. Histogenesis of the so-called " intravascular bronchioloalveolar tumour" [J]. J Pathol, 1979, 128 (3): 163-167.
  • 4Weldon-Linne CM, Victor TA, Christ ML, et al. Angio- genic nature of the " intravascular bronchioloalveolar tumor" of the lung: an electron microscopic study [ J ]. Arch Pathol Lab Med, 1981, 105 (4) : 174 - 179.
  • 5Weiss SW, Ishak KG, Dail DH, et al. Epithelioid heman-gioendothelioma and related lesions [ J ]. Semin Diagn Pathol, 1986, 3 (4) : 259 - 287.
  • 6Fletcher CD, Unni KK, Mertens F. WHO classification of tumours: pathology and genetics of tumours of soft tissue and bone JR]. Lyon, France: IARC, 2002: 11.
  • 7顾莹莹,刘芳,曾庆思,刘慕嫦.肺上皮样血管内皮瘤的临床病理观察[J].临床与实验病理学杂志,2006,22(1):32-35. 被引量：13
  • 8Shang A, Wang X. Pulmonary epithelioid haemangioendo- thelioma mimicking central lung cancer [ J ]. Respirology, 2009, 14 (3) : 452 - 455.
  • 9Cronin P, Arenberg D. Pulmonary epithelioid hemangioen- dothelioma: an unusual case and a review of the literature [J]. Chest, 2004, 125 (2):789-793.
  • 10Rosengarten D, Kramer MR, Amir G, et al. Pulmonary epithelioid hemangioendothelioma [ J ]. Isr Med Assoc J,2011, 13 (11):676 -679.

二级参考文献32

  • 1Weiss S W,Enzinger F M.Epithelioidhemangioendothelioma:A distinctive vascular tumor often mistaken for a carcinoma[J].Cancer,1982,50:970-981.
  • 2Kitaichi M,Nagai S,Nishimura K,et al.Pulmonary epitheloid haemangioendothelioma in 21 patients,including three with partial spontaneous regression[J].Eur Respir J,1998,12(1):89-96.
  • 3Bharadwaj R,Hejmadi R,Mistry R,et al.Pericardial effusion and raised CA-125 level--unusual manifestations of primary pulmonary epithelioid hemangioendothelioma[J].Indian J Cancer,1999,36(2-4):194-197.
  • 4Jang K Y,Jin G Y,Lee Y C,et al.Pulmonary epithelioid hemangioendothelioma:a tumor presented as a single cavitary mass[J].J Korean Med Sci,2003,18(4):599-602.
  • 5Kumazawa Y,Maeda K,Ito M,et al.Expression of glucocorticoid receptor and 11beta hydroxysteroid dehydrogenase in a case of pulmonary epithelioid haemangioendothelioma[J].Mol Pathol,2002,55(1):61-64.
  • 6Yi E S,Auger W R,Friedman P J,et al.Intravascular bronchioloalveolar tumor of the lung presenting as pulmonary thromboembolic disease and pulmonary hypertension[J].Arch Pathol Lab Med,1995,119(3):255-260.
  • 7Boudousquie A C,Lawce H J,Sherman R,et al.Complex translocation [7;22] identified in an epithelioid hemangioendothelioma[J].Cancer Genet Cytogenet,1996,92(2):116-1121.
  • 8Mendlick M R,Nelson M,Pickering D,et al.Translocation t(1;3;q25) is a nonrandon aberration in epithelioid hemangioendothelioma[J].Am J Surg Pathol,2001,25(6):684-687.
  • 9Vandenheede M,Salem T,Sayago I,et al.Clinical case of the month.Multiple pulmonary nodules.Epithelioid hemangioendothelioma[J].Rev Med Liege,1998,53(8):454-458.
  • 10Nagata N,Takatsu H,Sato Y,et al.Metastatic pulmonary epithelioid hemangioendothelioma with peculiar radiographic features[J].Respiration,1999,66(1):78-80.

共引文献25

同被引文献18

  • 1曾庆思,陈苓,顾莹莹.2例肺上皮样血管内皮瘤X线影像表现[J].广州医学院学报,2005,33(2):58-61. 被引量：3
  • 2Dail DH,Liebow AA,Gmelich JT, ct al. Intravascular,bronchiolar,and alveolar tumor of the lung ( IVBAT). Ananalysis of twenty cases of a peculiar sclerosing endolhelialtumor[J]. Cancer, 1983 ,51(3) : 452-464.
  • 3Corrin B,Manners B,Millard M,et al. Histogenesis of the so-called .. intravascular bronchioloalveolar tumour " [J]. JPathol, 1979,128(3) :163-167.
  • 4Weldon-Linne CM, Victor TA, Christ ML, et al. Angiogenicnature of the "intravascular bronchioloalveolar tumor" of thelung: an electron microscopic study [J]. Arch Pathol LabMed,1981,105(4) :174-179.
  • 5Weiss SW,Enzinger FM. Epithelioid hemangioendothelioma :a vascular tumor often mistaken for a carcinoma[J]. Cancer,1982,50(5):970-981.
  • 6Leleu 0, Lenglet F, Clarot C, et al. Pulmonary epithelioidhaemangioendothelioma : reports of three eases and a reviewof the literature[J]. Rev Mai Respir, 2010 ,27(7) : 778-783.
  • 7Amin RM. Hiroshima K, Kokubo T, et al. Risk factors andindependent predictors of survival in patients with pulmonaryepithelioid haemangioendothelioma. Review of the literatureand a case report[J]. Respirology, 2006 ,11(6) : 818-825.
  • 8Cronin P, Arenberg D. Pulmonary epithelioidhemangioendothelioma : an unusual case and a review of theliterature[J]. Chest,2004 ,125(2) ; 789-793.
  • 9Luburich P, Ayuso MC,Picado C,et al. CT of pulmonaryepithelioid hemangioendothelioma [J]. J Comput AssistTomogr,1994,18(4) :562-565.
  • 10Bagan P, Hassan M,Le Pimpec Barthes F,et al. Prognosticfactors and surgical indications of pulmonary epithelioidhemangioendothelioma: a review of the literature [ J ]. Ann.

引证文献2

二级引证文献2

癌症进展
2012年 第5期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部