摘要
目的通过检测血清总胆汁酸(TBA)水平,确定总胆汁酸在新生儿黄疸诊断治疗中的临床应用价值。方法采用循环酶速率法,检测生理性黄疸、病理性黄疸患儿TBA水平,同时对其肝功能相关指标进行测定。结果生理性黄疸组的DBIL、ALT、TBA低于病理性黄疸组(P<0.05),尤其是生理性黄疸组的DBIL和TBA值明显低于病理性黄疸组(P<0.01)。生理性黄疸的ALT异常率及TBA异常率明显低于病理性黄疸组(P<0.01)。结论血清TBA测定能较好地诊断病理性黄疸患儿,是反映不同程度的胆汁淤积、肝实质性损伤的重要指征,可为临床提供诊断和治疗依据。
Objective To discuss the clinical application value of total bile acid in the diagnosis and treatment of neonatal jaundice through the detection of total bile acid （TBA） level. Methods Enzymatic cyc- ling method was used to test serum total bile acids in physiologic jaundice and pathological jaundice and de- tect the index of liver function. The results were compared. Results The DB1L, ALT, TBA of physiological jaundice group were lower than pathological jaundice group（ P 〈 0.05 ）, especially the DBIL and TBA value （ P 〈0.01 ）. The abnormal ALT rate and abnormal TBA rate of physiological jaundice group were significant- ly lower than the pathological jaundice group （ P 〈 0.01 ）. Conclusion Serum TBA test can be used to diag- nose pathological jaundice babies well ,which can reflect the important index of different degrees of cholesta- sis and substantive liver damage, thus can provide reference for clinical diagnosis and treatment.
出处
《医学综述》
2012年第19期3306-3307,共2页
Medical Recapitulate
关键词
生理性黄疸
病理性黄疸
新生儿
总胆汁酸
Physiological jaundice
Pathological jaundice
Newborn
Total bile acid
