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磁共振帕金森指数对进行性核上性麻痹的诊治提示 被引量：5

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摘要 目的研究磁共振帕金森指数(magnetic resonance Parkinsonism index,MRPI)对进行性核上性麻痹(progressive supranuclear plasy,PSP)诊断及预后的提示价值。方法搜集临床PSP 8例,额颞叶痴呆(fron-totemporal dementia,FTD)5例,帕金森病(Parkinson’s disease,PD)10例,多系统萎缩(multiple system atrophy,MSA)6例,行MR检查并计算MRPI值;采用PSP评定量表(progressive supranuclear plasy rating scale,PSPRS)评分,并与MRPI值行相关分析;对患者进行电话随访,分析MRPI值与生存时间关系。结果 PSP组MRPI值显著高于其余各组,PSP组数值与各组进行t检验(PD组P=0.0024;FTD组P=0.0032;MSA组P=0.0028);PSP组MRPI值与PSPRS得分呈正相关(r=0.7946,经t检验P=0.017);以MRPI值18.175分为界值将PSP组分为两个亚组,亚组间平均生存时间无统计学差异(Log-Rank Test检验,P=0.308)。结论 MRPI可以提高PSP的诊断准确率。
作者 朱银伟 孙永安 陈俊 肖朝勇 何伟 时建铨 张楚楚 江炜炜 张颖冬 徐俊
机构地区 苏州大学附属常熟医院神经内科 北京大学附属第一医院神经内科 南京医科大学附属脑科医院神经内科 南京医科大学附属脑科医院影像科 南京医科大学附属南京市第一医院神经内科
出处 《中国神经精神疾病杂志》 CAS CSCD 北大核心 2012年第9期547-550,共4页 Chinese Journal of Nervous and Mental Diseases
关键词 MR帕金森氏指数 进行性核上性麻痹 诊断 预后
分类号 R445.2 [医药卫生—影像医学与核医学] R741 [医药卫生—神经病学与精神病学]
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参考文献15

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二级参考文献37

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共引文献11

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中国神经精神疾病杂志
2012年 第9期

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