摘要
目的探讨液基薄层细胞学检测(thin-prep cytologic test,TCT)在基层医院宫颈病变诊断中的意义。方法选取2009年9月—2011年9月行宫颈TCT检查的宫颈疾病患者6 596例,对检出意义不明确的非典型性鳞状细胞(atypical squa-mous cells of undetermined significance,ASC-US)以上病变的阳性患者再行宫颈活检,将TCT检查结果与组织病理学诊断进行对照分析。结果 6 596例患者的宫颈TCT检查结果中,阳性218例,占3.31%。TCT检出的ASC-US与组织病理学诊断的符合率为46.32%,低度鳞状上皮内病变(low-grade squamous intraepithelial lesion,LSIL)的符合率为70.83%,两者比较差异有统计学意义(P<0.05);高度鳞状上皮内病变(high-grade squamous intraepithelial lesions,HSIL)的符合率为86.67%与ASC-US的符合率比较差异有统计学意义(P<0.05)。结论 TCT检出病变级别越高,与组织病理学诊断的符合率越高,在基层医院中需联合病理活检进一步确诊。
bjective To investigate the significance of thin-prep cytologic test （TCT） in the diagnosis of cervical lesions in primary hospitals.Methods 6 596 patients who had received TCT were selected from September 2009 to September 2011. Cervical biopsies were carried out in those with more severe lesions who were positive for atypical squamous cells of undetermined significance （ASC-US）. TCT findings and histopathologieal diagnosis were compared afterwards.Results 6 596 eases of patients with cervical TCT test resulted positive for 218 cases, accounting for 3.31%. TCT detection of ASC-US and histopathologieal diagnosis coinci- dence rate was 46.32%, low-grade squamous intraepithelial lesion（LSIL） compliance rate of 70.83%, the difference was statistically significant（P〈0.05）; high-grade squamous intraepithelial lesionsquamous（HSIL） compliance rate of 86.67% with ASC-US line, the rate difference was statistically significant（P〈0.O5）.Conelusion The more serious the lesions is detected by TCT, the higher the co- incidence rate of TCT and histopathologic diagnosis. In primary hospitals, pathological biopsy should be used in conjunction to fur- ther confirm the diagnosis.
出处
《社区医学杂志》
2012年第15期3-5,共3页
Journal Of Community Medicine
