摘要
目的观察天麻熄风口服液治疗急性期脑梗死的临床疗效,探讨其对血凝指标、血液流变学的影响。方法将100例急性期脑梗死患者随机分为2组。对照组予以西医常规治疗,治疗组在对照组基础上加服天麻熄风口服液治疗。治疗2个疗程后观察比较2组患者治疗前后血凝指标[活化部分凝血酶时间(APTT)、凝血酶原时间(PT)]、血液流变学指标(全血高切黏度、全血低切黏度、血浆黏度)的变化,并进行疗效比较。结果治疗组总有效率92.31%,对照组66.67%,2组比较差异有统计学意义(P<0.05);2组治疗后血凝指标APTT、PT及血液流变学指标全血高切黏度、全血低切黏度、血浆黏度与本组治疗前比较差异有统计学意义(P<0.05);治疗组治疗后血凝指标APTT、PT及血液流变学指标全血高切黏度、全血低切黏度、血浆黏度与对照组比较差异有统计学意义(P<0.05)。结论天麻熄风口服液治疗急性期脑梗死临床疗效显著,能改善患者血凝状态,改善患者血液流变学,阻止脑梗死急性期进展,促进脑梗死患者功能的恢复。
Objective To observe the curative effect of Tianmaxifeng oral liquid on acute cerebral infarction,and explore the effect of Tianmaxifeng oral liquid on the hemagglutination indicators and hemorheology.Methods 100 patients with cerebral infarction were randomly divided into two groups.Control group received conventional western medicine therapy.Treatment group received Tianmaxifeng oral liquid on the basis of conventional western medicine therapy.The changes of the hemagglutination indicators（Activated partial thromboplastin time（APTT）,prothrombin time（PT）） and hemorheology（high shear blood viscosity,low shear viscosity,plasma viscosity） were observed before and after treatment.The therapeutic effect was compared.Results The total effective rate in treatment group（92.31%） after treatment was significantly higher than that in control group（66.67%,P〈0.05）.There were significant differences between before and after treatment on APTT,PT,high shear blood viscosity,low shear viscosity and plasma viscosity in two groups（P〈0.05）.There were significant differences between two groups on APTT,PT,high shear blood viscosity,low shear viscosity and plasma viscosity after treatment（P〈0.05）.Conclusion Tianmaxifeng oral liquid has obvious effect on acute cerebral infarction,can improve coagulation status and hemorheology of patients,prevent the progress of acute cerebral infarction,and promote the recovery of function in patients with cerebral infarction.
出处
《河北中医》
2012年第5期656-657,660,共3页
Hebei Journal of Traditional Chinese Medicine
关键词
脑梗死
血凝素类
血液流变学
中药疗法
Cerebral infarction
Hemagglutinin
Hemorheology
Traditional Chinese Medicine therapy
