摘要
目的探讨不同肠内营养输注方式之间返流误吸风险的差异。方法采用前瞻性随机自身前后对照实验。选择气管插管(双腔可冲洗)并机械通气患者30例,采用两种输注方式,持续泵入输注(14h、20h)和间歇泵入输注(输注90min暂停150min,5次/d),采集咽喉部及气管插管气囊上分泌物,检测胃蛋白酶含量来判断返流误吸风险,同时抽取胃残余量。结果持续输注14h比持续输注20h、间歇泵入输注其咽喉部、气囊上胃蛋白酶浓度高。持续输注20h与间歇输注胃蛋白酶浓度差异无显著意义。胃残余量与返流误吸呈显著正相关关系。结论间歇泵入输注方式较持续输注(20h)没有增加返流误吸风险,机械通气患者进行肠内营养时可尽早使用。
Objective To study the different risk of regurgitation and aspiration between different infusion ways. Method A prospective randomized self-contrast trial was employed to study 30 critically ill patients who had been inserted double cavity tracheal cannula (Dual-chamber washable). Two different infusion ways were used, continuous infusion (20 hour,14 hour), intermittent infusion(90 min infusion, pause 150 minutes, 5 times per day), collecting secretions of oropharynx and deposits of tracheal cannula air bag, pepsin assay as diagnostic criteria, siphoning gas- tric residual juice. Result Pepsin concentration of oropharynx and tracheal cannula air bag in continuous feeding regi- men(14 h) were bigger than intermittent feeding regimen and continuous feeding regimen(20 h). Differences of the latter two were not significant. The residual stomach volume and aspiration or regurgitation events had a significant positive correlation. Conclusion Patients with mechanical ventilation should use intermittent feeding regimen as soon as possible which didn't increase risk of aspiration and regurgitation events.
出处
《护士进修杂志》
2012年第16期1451-1453,共3页
Journal of Nurses Training
关键词
营养输注方式
胃残余量
返流误吸
胃蛋白酶
Nutrition infusion ways Gastric residual volume Regurgitation and aspiration Pepsin