摘要
目的探讨长时间(>5天)使用抗生素能否减少穿孔性阑尾炎术后腹腔脓肿的机率。方法回顾性分析157例穿孔性阑尾炎术后使用抗生素治疗的病例资料,根据术后使用抗生素时间长短分为观察组(>5天)和对照组(≤5天),比较两组术后腹腔脓肿的发生率,Logistic回归分析腹腔脓肿发生的危险因素。结果观察组和对照组术后腹腔脓肿发生率无明显差异(9.8%vs9.2%,P=0.84),回归性分析显示<3000mL生理盐水腹腔冲洗是术后腹腔脓肿形成的危险因素(OR=4.568,P=0.038)。结论长时间使用抗生素并不能减少穿孔性阑尾炎术后腹腔脓肿的机率,术中大量生理盐水(>3000mL)冲洗腹腔可减少术后腹腔脓肿的发生率。
Objective To evaluate the probability of prolonged antibiotic treatment in reducing intra-abdominal abscess after the operation of perforating appendicitis.Methods The clinical data of 157 patients with antibiotic treatment after appendectomy for perforated appendicitis were retrospectively analyzed.According to the use time of antibiotics,patients were divided into the observation group（duration 5 days） and the control group（duration ≤5 days）.The incidences of postoperative intra-abdominal abscess between two groups were compared.Univariate logistic regression analysis was performed to determine the risk factors of intra-abdominal abscess formation.Results The incidence of postoperative intra-abdominal abscesses was similar（9.9% vs.9.2%,P =0.84） between two groups.Regression analysis demonstrated that the volume of saline solution washing abdominal cavity 3 000 mL was a risk factor for abscess formation（OR = 4.568,P = 0.038）.Conclusions Prolonged antibiotics after surgery for perforated appendicitis can not reduce postoperative intra-abdominal abscesses formation,but saline solution 3 000 mL washing abdominal cavity can reduce the incidence of intra-abdominal abscess.
出处
《临床医学工程》
2012年第7期1118-1119,共2页
Clinical Medicine & Engineering
关键词
穿孔性阑尾炎
抗生素
腹腔脓肿
危险因素
Perforated appendicitis
Antibiotics
Intra-abdominal abscess
Risk factors
