摘要
CAX是一种通过质子梯度产生的能量运输协调再分配钙离子(Ca2+)等阳离子的转运蛋白,是Ca2+/Cation antiporter(CaCA)大家族的一个分化枝。植物CAXs属于CAX三大类的Ⅰ型CAX。大部分植物CAXs有11个跨膜区(TM)和5个典型的功能域,即N-端自抑制区域(NRR)、C-端功能区域、Ca2+功能域(CaD)、C功能域和D功能域。其中NRR存在于大部分CAX中,调节CAX的功能。以下综述了近年来国内外对CAX类蛋白的研究成果与进展,涉及到CAX家族的命名,亚家族的分类,CAX组织表达及亚细胞定位,特别是CAX的转运活性等研究。加强对CAX的研究对调节植物生长、提高农作物养分吸收和减轻土壤中污染物等有重要作用。
Cation/H＋ antiporters （CAXs） are a group of proteins that effiux Ca2＋ and other cations to maintain optimal ionic concentrations in cells, which are energized by the proton gradient. It is one of the five families that constitute the Ca2＋/cation antiporter （CaCA） superfamily. Plant CAXs is the type I of three major categories. Plant CAXs are characterized by 11 transmembrane （TM） domains and 5 regulatory domains-that is N-terminal autoinhi- bitory domains （NRR）, C-terminal domains, Ca2＋ domain （CAD）, C domain and D domain, and NRR exists in most CAXs to regulate the function of CAX. In this paper, the research progress in the classification, location, structure and function of CAXs in plants is reviewed, especially in the transporter activity of CAXs. The studies of CAXs play an important role in regulating plant growth, increasing crop nutrient uptake and reducing pollutants in soil.
出处
《基因组学与应用生物学》
CAS
CSCD
北大核心
2012年第3期303-309,共7页
Genomics and Applied Biology
基金
国家林业局948项目(2008-4-29)
黑龙江省杰出青年科学基金(JC200609)共同资助
关键词
CAX家族
结构
定位
功能
CAX family, Structure, Location, Function
