摘要
缺血后处理是在缺血预处理基础上提出的新概念,因其对器官缺血-再灌注损伤具有良好的保护作用,应用性强,且具有事后性,目前已成为研究保护器官缺血-再灌注损伤方面的热点。但缺血后处理的确切机制及有效诱导时间窗等问题尚不清楚。因此,我们就其发现、发展(远隔后处理、药物后处理)、对心脏、肺、肝、肾和脑等的保护、机制及诱导时间窗等研究新进展进行综述。
Ischemia postconditioning is a new concept based on ischemic preconditioning. It has become a hot topic in protection of ischemic-reperfusion injury because of its effective protection, relative ease of application, and postconditioning. However, its precise mechanisms and most effective application methods are still unclear. This review covers recent progress in the understanding, developments （in remote postconditioning and pharmacological postconditioning）, applications to the protection of heart, lung, liver, kidney, and brain, mechanisms and appropriate protocol of ischemic postconditioning.
出处
《中国胸心血管外科临床杂志》
CAS
2012年第3期309-313,共5页
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
关键词
缺血-再灌注损伤
心肌保护
肺保护
缺血后处理
药物后处理
Ischemic reperfusion injury
Myocardial protection
Lung protection
Ischemic postconditioning
Pharmacological postconditionin
