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新生儿缺氧缺血性脑病血糖、血皮质醇水平变化及临床意义 被引量:10

CHANGE AND CLINICAL SIGNIFICANCE OF BLOOD GLUCOSE AND SERUM CORISOL IN NEWBORNS WITH HYPOXIC ISCHEMIC ENCEPHALOPATHY
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摘要 目的 观察新生儿缺氧缺血性脑病 (HIE)血糖 ,血皮质醇水平变化 ,为临床治疗 HIE提供参考依据。方法 :对 10 0例 HIE患儿测定血糖、血皮质醇水平 ,并以30例正常新生儿作为对照。结果 :10 0例 HIE患儿中 ,中、重度组血糖水平均高于对照组 (P <0 .0 1) ,但轻度组血糖水平与对照组无显著差异 (P >0 .0 5 )。不论轻、中 ,重度组血皮质醇水平均高于对照组 (P <0 .0 0 1) ,且临床分度愈重 ,皮质醇水平愈高(P <0 .0 0 1)。结论 :在处理 HIE患儿时应严密监测血糖 。 To observe the blood glucose and serum cortisol level in newborns with hypoxic ischemic encephalopathy (HIE). To offer evidence for therapy. Methods: Blood glucose and serum cortisol were determined in 100 newborns with HIE and 30 healthy full term newborns for control. Results: Blood gluconse levels of moderate and severe group were significantly higher than that of light group (P<0.01). There were no significant differences between light group and the control (P>0.05). The serum cortisol levels measured from light, moderate and severe HIE groups were obviously higher than that of the control (P<0.001). Meanwhile, the more serious HIE, the higher level of serum cortisol (P<0.001). Conclusion: Close attention should be paid to the blood glucose level and using glucocorticoid When we treat HIE newborns.
出处 《新生儿科杂志》 2000年第1期12-13,共2页 The Journal of Neonatology
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