期刊文献+

中西医结合治疗对子宫肌瘤及内膜组织ER、PR、bax的影响

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摘要 目的:观察自拟化积汤对子宫肌瘤及内膜组织ER、PR、bax的影响。方法:选择明确诊断为子宫肌瘤的患者114例,随机选取57例作为治疗组,在西医常规治疗的基础上,采用自拟化积汤治疗,剩余57例子宫肌瘤患者作为对照组,采用西医常规治疗。取子宫肌瘤组织,免疫组化法检测肌瘤和内膜组织中雌、孕激素受体ER、PR和凋亡基因bax的表达。结果:对照组ER含量测定的阳性率为59.7%,治疗组为42.2%;对照组PR含量测定的阳性率为66.7%,治疗组为43.9%;对照组bax含量测定的阳性率为40.4%,治疗组为59.7%,两组比较,差异均有统计学意义(P<0.05)。结论:自拟化积汤联合戈舍瑞林能够使得相应的子宫肌瘤的ER和PR显著减少,同时能够促进子宫肌瘤的细胞凋亡。
作者 刘小玲
机构地区 湘雅医院
出处 《中医药导报》 2012年第5期37-39,共3页 Guiding Journal of Traditional Chinese Medicine and Pharmacy
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参考文献4

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