摘要
目的探讨维生素E辅助治疗儿童癫痫的临床应用价值。方法 66例癫痫患儿,分为观察组和对照组,每组33例。对照组给予托吡酯等常规抗癫痫药物治疗,观察组在常规服用抗癫痫药物基础上加用维生素E治疗。检测并比较2组患儿总抗氧化力(T-Aoc)及丙二醛(MDA)水平,比较2组患者治疗效果。结果经足疗程治疗后,观察组治疗总有效率(72.73%)明显高于对照组(48.48%),差异有统计学意义(P<0.05)。治疗后,观察组T-Aoc显著高于对照组,MDA明显低于对照组,差异均有统计学意义(P<0.05)。结论在常规抗癫痫治疗的基础上,应用维生素E辅助治疗,可以有效提升患者体内抗氧化能力,提高治疗有效率。
Objective To investigate the application value of vitamin E adjuvant therapy in children with epilepsy. Methods Sixty-six children with epilepsy were divided into control group and observation group,33 cases in each group.The patients in control group were treated with topiramate and other conventional anti-epileptic drugs.The patients in observation group were treated with vitamin E on the basis of anti-epileptic drugs.The total antioxidant（T-Aoc） and malondialdehyde（MDA） were tested and compared,the curative effect was also compared between the two groups. Results The total treatment effective rate of the observation group（72.73%）was significantly higher than the control group（48.48%）,there was statistically difference between the two groups（P0.05）.After treatment,compared with the control group,the T-Aoc of the observation group was significantly higher,the MDA level was significantly lower,there were statistically differences（P0.05）. Conclusion Basing on the conventional anti-epileptic treatment,vitamin E adjuvant therapy can effectively enhance the antioxidant capacity,improve treatment efficiency.
出处
《新乡医学院学报》
CAS
2012年第6期437-438,441,共3页
Journal of Xinxiang Medical University
关键词
癫痫
维生素E
总抗氧化力
丙二醛
epilepsy
vitamin E
total antioxidant
malondialdehyde
