期刊文献+

C反应蛋白联合白细胞检测在新生儿感染性肺炎中的临床价值评价 被引量:14

Evaluation of the clinical value of joint detection of C-reactive protein and white blood cells in neonates with infectious pneumonia
原文传递
导出
摘要 目的:评估C反应蛋白(CRP)联合白细胞(WBC)检测在新生儿感染性肺炎中的临床价值,为新生儿感染性肺炎的早期诊断和治疗提供依据。方法:以2009年7月~2011年6月入院的123例新生儿感染性肺炎患儿为研究组,以健康新生儿为对照组,分析CRP和WBC的变化。结果:新生儿感染性肺炎患儿CRP、WBC较健康新生儿增高,尤以细菌性感染患者为著(P<0.05)。细菌性肺炎感染患者治疗前后CRP和WBC变化差异有统计学意义(P<0.05),且CRP变化幅度大于WBC。结论:对于细菌性肺炎的早期诊断和治疗监测CRP是较WBC更为灵敏和可靠的指标,两者联合检测可提高新生儿感染性肺炎的早期诊断率。 Objective:To evaluate the clinical value of joint detection of C-reactive protein(CRP) and white blood cells(WBC) in neonates with infectious pneumonia,provide a basis for early diagnosis and treatment of neonatal infectious pneumonia.Methods:One hundred and twenty-three neonates with infectious pneumonia who were treated in the hospital from July 2009 to June 2011 were selected as study group,100 healthy neonates were selected as control group,the changes of CRP and WBC were analyzed.Results:The levels of CRP and WBC in the neonates with infectious pneumonia were higher than those in healthy neonates,especially the neonates with bacterial infection(P0.05);among the neonates with bacterial infection,there was significant difference in the levels of CRP and WBC before and after treatment(P0.05),and the change extent of CRP was larger than that of WBC.Conclusion:Compared with WBC,CRP is more sensitive and reliable for early diagnosis and treatment of neonatal infectious pneumonia,joint detection of WBC and CRP can improve the early diagnostic rate of neonatal infectious pneumonia.
出处 《中国妇幼保健》 CAS 北大核心 2012年第10期1490-1491,共2页 Maternal and Child Health Care of China
关键词 CRP WBC 新生儿 感染性肺炎 C-reactive protein White blood cell Neonate Infectious pneumonia
  • 相关文献

参考文献5

二级参考文献36

共引文献103

同被引文献133

  • 1苏磊,周殿元,唐柚青,文强,白涛,孟繁苏,唐丽群,段鹏凯.CD14^+单核细胞人白细胞DR抗原在脓毒症早期检测中的临床意义[J].中国危重病急救医学,2006,18(11):677-679. 被引量:21
  • 2林洪远,管向东,周立新,艾宇航,王可富.乌司他丁、α1胸腺肽联合治疗严重脓毒症——一种新的免疫调理治疗方法的临床研究[J].中华医学杂志,2007,87(7):451-457. 被引量:100
  • 3Satou G,Giamelli J,Gewitz M.Kawasaki disease diagnosis,man- agement and long-term implications[J]. Cardiol Rev,2007,15(4): 163-169.
  • 4Lodahl D,Schroder H. Procalcitonin adds to diagnosis, but does not reduce initial antibiotics in febrile neutropenic chinren[J].Dan Med Bull,2011,3(58):A4233.
  • 5Prucha M, Zazula R, Muller M, et al. TREM-1 expression on monocytes is not a parameter specific for infectious etiology of systemic inflammatory response syndrome[J]. Prague Med Rep, 2011,112(3):205-215.
  • 6Dellinger R P, Levy M M, Rhodes A, et al. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012[J]. Crit Care Med, 2013,41(2): 580-637.
  • 7Knaus W A, Draper E A, Wagner D P, et al. APACHE II: a severity of disease classification system[J]. Crit Care Med, 1985:1(10):818-829.
  • 8Liu B. Chen Y X, Yin Q, et al. Diagnostic value and prog- nostic evaluation of Presepsin for sepsis in an emergency de- partment[J]. Crit Care, 2013,17(5):R244.
  • 9Oberholzer A, Oberholzer C, Moldawer L L. Sepsis syndromes: understanding the role of innate and acquired immunity[J]. Shock, 2001,16(2):83-96.
  • 10陈宏础,王鸿利.全国临床检验操作规程[M].南京:东南大学出版社,2006:133.

引证文献14

二级引证文献165

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部