摘要
近年来，随着核酸及核酸类似物、聚乙二醇干扰素仅等抗病毒药物的问世，使得慢性乙型肝炎临床抗病毒治疗取得了明显发展，同时对乙型病毒肝炎的实验室检测也提出了新的要求，促进了实验室诊断技术的发展。本研究着重讨论临床抗病毒治疗中乙型肝炎病毒DNA定量检测的应用和重要性，指出HBVDNA的定量检测病毒学应答对于判定抗病毒疗效、调整临床抗病毒治疗方案、停药后随访及预测预后等有重要意义。
In recent years, antiviral therapy for chronic hepatitis B infected patients has achieved great development along with the invention of nucleos （ t ） ide, nucleos （ t ） ide analogues, interferon α and pegylated interferon α. The development of antiviral medicine also proposes new demands for the clinical diagnosis and therefore promotes the development of laboratory diagnostic techniques in the detection of chronic hepatitis B. In this review, we focused on the clinical application in the quantitive detection of HBV DNA, and its significance on clinical evaluation, treatment options, follow-up and prognosis in antiviral therapy.
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2012年第2期117-121,共5页
Chinese Journal of Laboratory Medicine
