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不同人工泪液对体外培养的人角结膜上皮细胞的毒性作用比较 被引量:11

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摘要 干眼是泪液分泌量不足、泪膜稳定性受损所致的眼部疾病[1-2].流行病学研究表明,在世界范围内,干眼发病率很高,与老龄、妇女围绝经期、配戴隐形眼镜及自身免疫性疾病等有关[3-5],其中亚洲人群中发病率约为17% ~ 33% [6-9],而白种人发病率相对较低,约为7%~14.6%[3,10].目前,干眼最常用的治疗方法是眼表滴用人工泪液,由于干眼是慢性疾患,大部分患者需长期用药,因此其长期疗效和安全性值得关注.本研究比较了不同成分的人工泪液对体外培养的人角膜和结膜上皮细胞的毒性作用,以期为临床用药提供试验依据.
出处 《中华眼科杂志》 CAS CSCD 北大核心 2012年第2期170-172,共3页 Chinese Journal of Ophthalmology
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