摘要
观察了鳖甲煎口服液对实验性肝纤维化的治疗作用。应用四氯化碳复合因素造模后选取血清谷丙转氨酶 (AL T)、碱性磷酸酶 (AL P)、乳酸脱氢酶 (L DH)活性、透明质酸 (HA)、血清白蛋白 (AL B)及组织学变化作为测定指标并与秋水仙碱作比较 ,进行实验。结果表明鳖甲煎口服液与金匮鳖甲煎丸一样对实验性肝纤维化有明显的治疗作用。它能提高血清 AL B含量 ,使 AL T、 AL P、 L DH活性下降 ,HA含量下降 ,门脉高压降低 ,调整免疫功能而使脾重减轻。
Observe Biejia Jian Oral Liquid's cure to experimental liver fibrosis.After making the model with carbon tetrachloride combined factor,take the activities of serum glutamic pyruvic transaminase(ALT),alkaline phosphatase(ALP)and lactic dehydrogenase(LDH),the histological changes,hyaluronidase(HA) and serum albumin(ALB)as the measuring indexes,compared to colchicine,then make the experiment.The result shows Biejia Jian Oral Liquid has the same cure as Biejia Jian Wan to increase the content of Alb,reduce the activities of ALT,ALP and LDH and the content of HA,lower portal hypertension and lighten the heavy spleen through adjusting immunologic function.
出处
《浙江中医学院学报》
2000年第1期58-61,共4页
Journal of Zhejiang College of Traditional Chinese Medicine
基金
浙江省教委资助课题!编号 96 0 10
关键词
鳖甲煎口服液
肝纤维化
中医药疗法
Bie jia Jian Oral Liquid,liver fibrosis,experimental study
