摘要
目的探讨小剂量辛伐他汀治疗早期冠状动脉硬化性心脏病(冠心病)的临床疗效。方法选取我院2009年8月～2011年4月收治的110例初诊冠心病患者的临床资料,两组患者均采用常规治疗,治疗组患者常规治疗的基础上加用辛伐他汀治疗,随访6个月,比较两组患者颈动脉斑块、血脂及FAS改变情况。结果治疗组患者颈动脉粥样斑块、血脂、FAS改变均优于对照组,比较差异有统计学意义(P<0.05)。结论应用辛伐他汀治疗早期冠心病,有抗动脉粥样硬化形成的作用,效果满意。
Objective To investigate the low-dose simvastatin treatment of early coronary heart disease （CHD） clinical efficacy. Methords A hospital in August 2009-April 2011 treated 110 patients with newly diagnosed coronary heart disease in patients with clinical data, two groups of patients were treated with conventional therapy, patients treated with conventional therapy based on the use of simvastatin treatment, follow-up 6 months, compared two groups of patients with carotid artery plaque, blood lipids and FAS to change the situation. Results The patients with carotid artery plaque, blood lipids, FAS to change than the control group, the difference was statistically significant （P〈0.05）. Conclusion Simvastatin treatment of early coronary heart disease, have anti- atherosclerosis formation, results were satisfactory.
出处
《心血管病防治知识（学术版）》
2012年第1期15-17,共3页
Prevention and Treatment of Cardiovascular Disease
关键词
辛伐他汀
早期冠心病
FAS
动脉粥样斑块
血脂
simvastatin
early coronary heart disease
FAS
atherosclerotic plaque
lipids
