摘要
本研究旨在验证超声造影(CEUS)检测血液透析通路再循环(AR)和血液透析通路血流量(Qa)的可行性及准确性,分析影响测量准确性的相关因素。通过建立通路循环及透析回路体外管道模型,运用超声造影技术检测动静脉管路的正反接法,针头朝向血流及背向血流等不同情况下对AR及Qa测定的影响。依据指示剂稀释原理计算再循环率R值及Qa,分析测量值与真实值之间的相关性及一致性。结果显示R测量值与R理论值相关性良好(r=0.57,P=0.038,Qa>Qb;r=0.95,P=0.001,Qa<Qb),Bland-altman检验显示测量值与真实值一致性良好,针尖朝向血流绝对错误率(K值)较低。可见CEUS有望成为一项新技术运用于透析AR及Qa的检测。
To evaluate the feasibility and accuracy of contrast-enhanced ultrasonography（CEUS） for the measurement of hemodialysis access recirculation（AR） and access flow rate（Qa）,a two pump system was used to simulate access and dialyzer flow.AR and Qa under different conditions,such as reversal connection of dialysis lines and the needle orientation,were compared with each other.The value of access flow and recirculation flow were calculated based on the formulas introduced in this paper,and the correlation and consistency between true flow rate and calculated values were analyzed.The measured R correlated well with true value of flow rate（r=0.57,P=0.038,QaQb;r=0.95,P=0.001,QaQb）.The Bland-altman test showed good agreement between the calculated value based on CEUS and true values.The CEUS can be used as a new advanced technology for AR and Qa measurement.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2012年第1期84-88,共5页
Journal of Biomedical Engineering
关键词
验证超声造影
血液透析
通路再循环
通路血流量
Contrast-enhanced ultrasonography（CEUS）
Hemodialysis
Access recirculation（AR）
Access flow rate（Qa）
