摘要
目的:探讨老年急性脑梗死患者同型半胱氨酸水平与预后的关系。方法:选择80例老年急性脑梗死患者作为观察组,同期选取60例健康体检者为对照组。采用循环酶法测定血浆同型半胱氨酸水平,乳胶增强免疫比浊法测定高敏C-反应蛋白(hs-CRP),比较两组血清同型半胱氨酸、hs-CRP水平以及二者与脑梗死患者病情严重程度的关系。结果:观察组血清同型半胱氨酸、hs-CRP水平明显高于对照组,差异有统计学意义(P<0.01);观察组轻型、中型及重型脑梗死组患者同型半胱氨酸、hs-CRP水平逐渐升高,差异有统计学意义(P<0.05)。结论:老年急性脑梗死患者血清同型半胱氨酸、hs-CRP水平显著升高,且与患者病情相关,表明二者参与了动脉粥样硬化形成发展过程,二者联合检测可作为判断患者预后的重要指标。
Objective： To explore the relation of homocysteine and prognosis of elder acute cerebral infarction.Methods：A total of 80 elder cases with acute cerebral infarction were selected as experiment group,and 60 healthy persons as controls.Cyclophorase was used to detect homocysteine and immunoturbidimetry was performed to detect C-reaction protein（hs-CRP）.The level of homocysteine and hs-CRP of two groups and the relation of homocysteine and severity were studied.Results：Serum levels of homocysteine and hs-CRP in experiment group were significantly higher than those in control group（P0.01）;Homocysteine and hs-CRP levels were significantly higher in severe group than medium group and mild group（P0.05）.Conclusions：Homocysteine and hs-CRP levels greatly increase in elder acute cerebral infarction and have a relation with severity.They participate in the progress of atherogenesis and can be important index for predicting the prognosis.
出处
《海南医学院学报》
CAS
2012年第2期187-188,192,共3页
Journal of Hainan Medical University
基金
中国高校医学期刊临床专项资金项目(11221012)~~
