摘要
以丙烯醛为原料,通过单因素实验,建立了优化的温和液相反应条件,合成3-甲基吡啶的优化工艺条件为:以乙二醇单丁醚为溶剂,反应温度140℃,料比n(丙烯醛)∶n(乙二醇单丁醚)∶n(乙酸铵)=1∶33∶8,以正丁酸为稀释剂配成w(丙烯醛)=15%的正丁酸溶液,m(丙烯醛)∶m(SO42-/TiO2-HZSM-5)=1∶1.4。在优化条件下,实现了丙烯醛转化率100%,3-甲基吡啶选择性49.92%。
This paper is to report an optimum preparation process of 3-picoline by mild liquid phase reaction of acrolein based on single factor design method. The reaction was carried out in the solvent of ethylene glycol monobutyl ether at 140 ℃ of temperature for 1 h,the mole ratio of aerolein and acetic ammonium and ethylene glycol monobutyl ether being 1：8：33, the mass ratio of aerolein and catalyst SO42-/TiO2-HZSM-5 being 1：1.4, and the mass percent of acrolein in n-butyric acid being 15%. Under the optimized conditions, the conversion rate of aerolein reached 100% and the yield of the selectivity of 3-picoline reached 49.92%.
出处
《精细化工》
EI
CAS
CSCD
北大核心
2012年第1期82-85,共4页
Fine Chemicals
基金
国家自然科学基金项目(20975094)~~
关键词
3-甲基吡啶
丙烯醛
液相反应
工艺优化
精细化工中间体
3-picoline
aerolein
liquid phase reaction
process optimization
fine chemical intermediates
