摘要
目的:了解蚌埠地区抗菌药物致不良反应(ADR)的发生情况。方法:对2009-2010年蚌埠地区上报的抗菌药物致ADR报告,按性别、年龄、给药途径、药品类别、ADR累及器官或系统及临床表现等进行统计、分析。结果:ADR涉及的抗菌药物共107种,2791例/次,发生频次以头孢菌素类居首位(占31.31%),其次为喹诺酮类和青霉素类;主要的ADR类型为皮肤及其附件损害,占40.58%;严重ADR11例。结论:临床应规范抗菌药物的临床应用,以减少其ADR的发生率。
OBJECTIVE： To investigate the situation of antibiotics-induced adverse drug reactions （ADR） in Bengbu area. METHODS： According to gender, age, route of administration, drug category, organs or systems involved in ADR, clinical manifestations, and so on, reports of antibiotics-induced drug adverse reactions reported in Bengbu from 2009 to 2010 were analyzed statistically. RESULTS： 107 antibiotics were involved in ADR for 2 791 times. ADR most occurred in cephalosporin antibiotics （31.31% ）, followed by quinolones and penicillins. Primary ADR type was lesion of skin and its appendents, which accounted for 40.58% of the total. 11 cases suffered from serious ADR. CONCLUSIONS： Clinical application of antibiotics should be standardized to reduce the incidence of ADR.
出处
《中国药房》
CAS
CSCD
2012年第2期150-152,共3页
China Pharmacy
基金
2010年蚌埠市医疗卫生科技计划项目(201003022)
