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稀释碘伏对人结肠癌细胞株SW480体外生长的影响 被引量:5

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摘要 目的观察稀释碘伏对人结肠癌细胞株SW480体外生长的影响。方法体外培养SW480,分别用0.05%、0.025%、0.01%的碘伏处理,MTT法测算细胞生长抑制率,PI染色流式细胞术分析细胞凋亡率。结果 0.05%、0.025%、0.01%的碘伏对SW480的生长抑制率分别为84.0%、84.3%8、4.5%,三者相比,P>0.05;0.01%的碘伏分别作用13、5、min后,SW480的生长抑制率分别为82.4%8、3.6%8、4.0%,三者相比,P>0.05。0.01%碘伏处理SW480细胞1 min即可诱导其凋亡,凋亡率达78.3%。结论稀释碘伏在体外对人结肠癌细胞具有明显的生长抑制及诱导凋亡的作用。
出处 《山东医药》 CAS 北大核心 2011年第42期86-87,共2页 Shandong Medical Journal
基金 陕西省卫生厅科研基金资助项目(2008H039) 延安市科学技术研究基金资助项目(2008ks-30)
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参考文献5

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