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凯时与腺苷钴胺联合治疗2型糖尿病周围神经病变临床观察 被引量:2

Clinical Observation of Type 2 Diabetic Peripheral Neuropathy Treated with Lipo PGE1 Combination with Cobamamide
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摘要 目的:观察凯时与腺苷钴胺联合治疗糖尿病周围神经病变的疗效。方法:选择确诊的2型糖尿病患者合并周围神经病变患者83例,随机分为治疗组43例,对照组40例。治疗组予静脉滴注生理盐水100ml,凯时注射液10ug/日静脉入壶、肌肉注射腺苷钴胺1.5mg/日,连续治疗10天,改为口服腺苷钴胺治疗。对照组只予口服腺苷钴胺治疗。两组均连续治疗30天。观察两组治疗前后症状改善情况。结果:两组临床症状均有改善,治疗组总有效率为86.0%,对照组总有效率为52.5%,两组比较,差异有显著性(P<0.05)。结论:凯时联合腺苷钴胺治疗糖尿病周围神经病变有良好疗效。 Objective:To observe the clinical efficacy of combined therapy of type 2 diabetic neuropathy with Lipo PGEI and cobamamide,Methods:83 DPN patients were randoinly divided into two groups,The treatment group was treated with alprostadil 10ug and physiological saline 10Oral ivgtt qd and cobamamide 1.5mg im.qd. After the 10-day treatment,the trestment group was treated cobamamide .The control group was treated with cobamamide. All the treatment was based on .Time of therapy was 30 days, Results:The total effective rate of the treatment group was 86,0%, and of the control group was 52.5%,The treatment group was significantly higher than the control group. Conclusion:Atprostadil combined cobamamide has a good curative effect on DPN.
作者 张伟
出处 《中国医药导刊》 2011年第8期1366-1367,共2页 Chinese Journal of Medicinal Guide
关键词 前列地尔 腺苷钴胺 糖尿病周围神经病变 Alprostadil Cobamides Diabetic peripheral neuropathy
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