摘要
荧光原位杂交技术(FISH)技术是一门新兴的分子细胞学遗传技术,具有快速、安全、高灵敏度及探针可长期保存等优点,在分子细胞遗传学、肿瘤生物学、产前诊断等领域已得到广泛应用。从FISH与常规宫颈癌检测技术比较、荧光探针类型及标记方法和在宫颈癌中的应用做简要综述。
fluorescence in situ hybridization(FISH) is a new and developing molecular cytogenetic approach with a number of advantages over conventional approaches,including improved speed,safty,sensitivity,specificity and is able to long-term preserve the probe.FISH has been applied in molecular cytogenetic detection,oncobiology detection and prenatal diagonsis.This review introdues the comparison of FISH and routine method of detection of the cervical cancer、the prode type、marking methed and the application of FISH in the cervical cancer.
出处
《中华中医药学刊》
CAS
2011年第10期2263-2265,共3页
Chinese Archives of Traditional Chinese Medicine
基金
浙江省医药科技基金资助项目(2006A122)