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艾燃烧生成物组分固相微萃取气相色谱质谱法定性分析 被引量:61

Qualitative analysis on components of moxa combustion products by solid-phase microextraction-gas chromatography-mass spectrography
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摘要 目的深入研究艾灸效应机制,为艾灸安全性研究奠定基础。方法采用固相微萃取气相色谱质谱联用(SPME-GC-MS)技术对蕲艾绒燃烧生成的烟气(即艾烟)进行定性分析。结果共分离出61个峰,其中鉴定出26种成分,检出物质分3部分,0~10 min为有呋喃结构的物质,10~40 min基本为芳香族化合物4,0~70 min为酯类、烷烃或含羟基类化合物。结论艾燃烧生成物中多数成分可用于香精香料,有少数成分在高浓度时有一定的毒性;研究艾燃烧生成物的安全性,需要进一步对检出的成分进行定量分析。 Objective To study deeply the effective mechanism of moxibustion, and lay a foundation for the research on safety of moxibustion. Methods The combination technique of solid-phase microextraction-gas chromatography-mass spectrography (SPME-GC-MS) was used to analyse qualitatively the moxa smoke produced after moxa combustion. Results There were totally 61 peaks separated, and among them 26 components were identified, which consisted of three parts : components with furan structure at 0 - 10 minutes, aromatic compounds at 10 - 40 minutes, and esters, alkanes or hydroxyl-containing compounds at 40 -70 minutes. Conclusion The products of moxa combustion are mostly essence and aroma, and a few of them will have some toxicity in a higher concentration. It is necessary to analyse quantitatively the detection components for studying on the safety of moxa combustion products.
出处 《北京中医药大学学报》 CAS CSCD 北大核心 2011年第9期632-636,共5页 Journal of Beijing University of Traditional Chinese Medicine
基金 国家重点基础研究发展计划(973计划)项目(No.2009CB522906)
关键词 艾燃烧生成物 艾烟 苯酚 固相微萃取-气相色谱-质谱联用 moxa combustion products moxa smoke phenol combination of solid-phase .microextraction-gas chromatography-mass spectrography
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