摘要
目的:观察岩舒注射液联合PP方案治疗晚期非小细胞肺癌的近期疗效和毒副反应。方法:紫杉醇(PTX)150mg/m2,第1天静滴;顺铂(DDP)25mg/m2第1,23,天静滴,21天为1周期,2周期后进行疗效评定。治疗组在化疗同时应用岩舒注射液20ml,静脉滴注,每日1次,连用14天,2疗程后进行评定。结果:治疗组近期总有效率为42.59%,对照组为31.48%,两者差异无统计学意义(p>0.05)。治疗组胃肠道反应及骨髓抑制较对照组减轻,两者有统计学意义(p<0.05)。结论:岩舒注射液联合PP方案化疗治疗晚期非小细胞肺癌疗效较好,毒副反应轻。
OBJECTIVE： To observe the short-time efficary and toxic side effects of Yanshu Injection combined with PP regimen to treat patients with advanced non-small cell lung cancer（NSCLC）.METHODS： Paclitaxel（PTX） 150mg/m2 intravenous drip,d1;Cisplatin（DDP） 25mg/m2 intravenous drip d1-3,One cycle lasted 21 days.Efficary was evaluated after 2 cycles.Treatment group combined with Yanshu Injection 20ml intravenous drip qd for 14 days.Effect was evaluated after 2 cycles.RESULTS： The total shot-time effective rate is 42.59% in the treated group,while 31.48 % in the control group.But the difference between the two groups on therapeutic effect showed no significance（p0.05）.The hematological toxicity and gastrointestinal reactions in the treated group were lower than those in the control group with combined significanct difference（p0.05）.CONCLUSION： When used to treat patients with advanced NSCLC,Yanshu Injection combined with PP regimen were more effective and with lower toxic side effects.
出处
《内蒙古中医药》
2011年第18期23-24,共2页
Inner Mongolia Journal of Traditional Chinese Medicine
关键词
岩舒注射液
非小细胞肺癌
近期疗效
毒副反应
Yanshu Injection
Non-small cell lung cancer
Short-time efficary
toxic side effects
