摘要
目的探讨甲型H1N1流感轻症患者流行病学和临床特征。方法对病原学诊断为甲型H1N1流感的患者344例的临床资料进行回顾性分析,对其主要临床表现、体格检查、血细胞计数等项目与甲型H1N1流感病毒检测阴性的患者进行比较。结果临床表现方面,病原学诊断为甲型H1N1流感的患者与甲型H1N1流感病毒检测阴性的患者相比,咳嗽与咯痰症状比较突出(P<0.01);咽部充血与扁桃体肿大所占比例亦高于阴性组(P<0.01);甲型H1N1病毒核酸阳性组的白细胞计数、中性粒细胞计数明显低于阴性病人(P<0.01),淋巴细胞计数亦低于阴性组(P<0.05)。确诊甲型H1N1流感患者中,发病年龄以18～30岁所占比例最大,共248例,占72.09%。结论甲型H1N1流感患者以中青年为主;对甲型H1N1流感患者早期临床特征与血细胞计数的分析,有利于为甲型流感的早期诊断提供临床依据。
Objective To investigate the epidemiological and clinical features of 344 influenza A（H1N1）case with light symptoms.Methods The clinical data of 344 influenza A（H1N1）cases confirmed by pathogenic diagnosis were retrospectively analyzed including clinical features,results of physical examination and laboratory tests and compared with those negative for influenza A virus（H1N1）.Results Compared with those negative for influenza A virus（H1N1）the symptoms of cough and with phlegm was obviously observed in influenza A（H1N1）patients,showing significant differences（P0.01）.The percentage of throat congestion and antiadoncus was significantly higher in the influenza A（H1N1）cases than that of those negative for influenza A virus（H1N1）（P0.01）.The WBC count,neutrophil count and lymphocyte count in patients positive for influenza A virus cnucleic acid were significantly lower than those of the negative group（P0.01 and P0.05）.There 72.09% of the confirmed influenza A（H1N1）cases wer in the age group of 18-30 years.Conclusion Most of the influenza A（H1N1）cases were those at their prime of life and clinical manifestations/signs and hematological test results were the basis for early diagnosis of the disease.
出处
《中国热带医学》
CAS
2011年第8期958-959,共2页
China Tropical Medicine
基金
2009年中医药行业专项资助(No.200907001-2B)
关键词
甲型流感
流行病学
临床特征
体征
白细胞计数
Influenza A（H1N1）
Epidemiology
Clinical features
Sign
White cell count
