摘要
目的:探讨上尿路移行细胞癌病理特点的性别差异。方法:对597例(男性253例、女性344例)于北京大学第一医院行手术治疗并经病理证实为上尿路移行细胞癌的患者进行单因素分析,比较上尿路移行细胞癌病理特点的性别差异。结果:本组患者平均年龄67岁(20～94岁)。单因素分析显示,与男性相比,女性患者的肿瘤体积更小(P=0.017),局部进展的比例较低(P<0.001),淋巴结转移比例较低(P=0.022),而在年龄构成、肿瘤数目和分级上,不同性别之间差异无统计学意义。结论:我国UUTUC患者多为女性,且与男性相比,女性患者肿瘤局部进展的风险相对较低,表明其可能具有独特的临床病理特点。
Objective： To assess the sex differences in pathologic characteristics of Chinese patients with upper urinary tract urothelial carcinoma（UUTUC）.Methods： Between January 2004 and December 2010,597 patients（253 men and 344 women） underwent surgical management at Peking University First Hospital for pathologically proven UUTUC.We reviewed pathological data from these patients,and used univariate analysis to determine sex differences.Results： Of the 597 consecutive cases,mean age was 67 years ranging from 20 to 94 years.Univariate analyses showed that female patients had less proportion of large tumor（P=0.017）,local advanced tumor（P〈0.001） and lymph node metastasis（P=0.022）.No significant sex-related differences were found in the age,tumor grade,and tumor number.Conclusion： In Chinese UUTUC patients,female patients were more common.Females are less likely to have more advanced pathologic stage than males.
出处
《北京大学学报（医学版）》
CAS
CSCD
北大核心
2011年第4期522-524,共3页
Journal of Peking University:Health Sciences
