摘要
目的探讨躯体感觉诱发电位（SEP）对神经根型颈椎病（CSR）的早期诊断价值。方法对65例病程3个月内的CSR患者（病例组）进行正中神经SEP（SEPm）的检测，并选取30例健康志愿者作为对照组。所有患者均行颈椎MRI检查，比较SEPm与MRI的检查结果，病程12个月时复查SEPm及MRI。结果病例组SEPm检测N11、N13峰潜伏期及N9-N13峰间期在病程3个月内分别为（12．92±0．97）、（14．81±1．16）、（4．45±0．65）ms，在病程12个月时分别为（14．20±1．06）、（16．35±1．75）、（5．62±0．88）ms，均较对照组的（11．65±0．69）、（13．26±0．78）、（3．56±0．31）ms明显延长（P〈0．05），且病程12个月时较病程3个月内延长（P〈0．05）。病例组在病程3个月内的SEPm阳性率为87．69％（57，65），明显高于MRI的70．77％（46／65），两者阳性率比较差异有统计学意义（r=4．35，P〈0．05）；在病程12个月时SEPm、MRI阳性率分别为90．77％（59／65）、81．54％（53／65），两者阳性率比较差异无统计学意义（r=1．56，P〉0．05）。结论SEP对CSR的早期诊断有重要价值，可作为常规检查手段。
Objective To investigate the value of somatosensory evoked potentials （SEP） in early diagnosis of cervical spondylotic radiculopathy （CSR）. Methods The median nerve SEP （SEPm） was examined in 65 cases of CSR （experimental group ）, and was compared with 30 controls （control group）. All the patients were examined by MRI of the cervical spine which were compared with SEPm. All cases were followed up 12 months, at the same time MRI and SEPm were examined repeatedly. Results The experimental group with CSR had significantly prolonged peak latency （PL） of Nll and N13 wave and interpoak latency（IPL） of wave N9-N13 within 3 months [（ 12.92 ±0.97）, （14.81 ± 1.16）, （4.45±0.65） ms] and at the 12th month [（14.20 ± 1.06）, （16.35± 1.75）, （5.62 ±0.88） ms] compared with those of control group [ （ 11.65 ± 0.69 ）, （ 13.26 ±0. 78 ）, （3.56 ± 0.31 ） ms ] （ P 〈 0.05 ）. The PL of N 11 and N 13 wave and IPL of wave N9-N13 significantly prolonged at the 12th month compared with those within 3 months. SEPm provided more sensitive modality for the diagnosis[ 87.69%（57/65 ） ] of CSR within 3 months than that of MRI [70.77% （46/65）] （X2 = 4.35 ,P 〈 0.05）. While there was no significant difference in sensitive between SEPm [ 90.77% （59/65） ] and MRI [ 81.54% （53/65） ] at the 12th month （ X2 = 1.56, P 〉 0.05）. Conclusion SEP is valuable for the early diagnosis of CSR and may be clinically utilized as a sensitive indicator of CSR.
出处
《中国医师进修杂志》
2011年第23期24-26,共3页
Chinese Journal of Postgraduates of Medicine
关键词
诱发电位
躯体感觉
颈椎病
早期诊断
Evoked potentials, somatosensory
Cervical spondylosis
Early diagnosis
