摘要
目的:观察硝酸甘油联合小剂量多巴胺治疗慢性肺源性心脏病心力衰竭的临床疗效。方法:将我院2008年2月-2010年12月收治的慢性肺源性心脏病心力衰竭患者68例,随机均分为试验组和对照组。对照组采取常规抗感染、氧疗、化痰利尿、止咳平喘以及对症治疗等处理,其中心率每分钟高于100次者配合去乙酰毛花苷注射液0.2mg,静脉推注;试验组在常规治疗基础上给予硝酸甘油6～10mg+多巴胺20mg,qd,治疗7～10d。比较2组临床疗效及住院天数。结果:试验组的总有效率(97.06%)高于对照组(67.65%),2组比较差异有统计学意义(P<0.05);试验组平均住院天数少于对照组(P<0.05)。2组均未见严重不良反应。结论:硝酸甘油联合小剂量多巴胺治疗慢性肺源性心脏病心力衰竭疗效确切,安全性较好。
OBJECTIVE：To observe clinical efficacy of nitroglycerin combined with dopamine in the treatment of heart failure of chronic pulmonary heart disease. METHODS： 68 patients with heart failure of chronic pulmonary heart disease were randomly divided into experimental group and control group from Feb. 2008 to Dec. 2010 in our hospital with 34 cases in each group. Control group was given conventional treatment, which included anti-infection, oxygen therapy, diuretic phlegm, relieving cough and asthma, and patients with higher heart rate （100·min-1） received cedilanid 0.2 mg, intravenous injection addtionally. Experimental group received nitroglycerin 6～10 mg combined with dopamine 20 mg on the basis of control group,qd,treat 7～10 d. The clinical efficacy and the hospital stay time were compared between 2 groups. RESULTS： The total effective rate of experimental group was 97.06%, which was higher than 67.65% of control group, there was statistical significance （P0.05）; the hospital stay time in experimental group was shorter than in control group （P0.05）. There were no serious ADR in both group. CONCLUSION： Nitroglycerin combined with dopamine is effective and safe in the treatment of heart failure of chronic pulmonary heart disease.
出处
《中国药房》
CAS
CSCD
北大核心
2011年第32期3015-3016,共2页
China Pharmacy
关键词
硝酸甘油
多巴胺
慢性肺源性心脏病
心力衰竭
疗效
Nitroglycerin
Dopamine
Chronic pulmonary heart disease
Heart failure
Clinical efficacy
