摘要
目的:探讨贝那普利联合缬沙坦治疗糖尿病肾病的临床效果。方法:217例早期DN患者被随机分为A,B和C组。三组均给予常规治疗,A组给予贝那普利治疗,B组给予缬沙坦治疗,C组给予联合治疗。结果:治疗半年后,三组血清肌酐(Cr)、微量白蛋白尿率过滤(UAER),尿素氮(BUN)均指标均有不同程度的改善,且C组改善效果最为显著(P<0.05)。结论:贝那普利联合缬沙应用于糖尿病肾病患者,效果显著,安全性高,是值得考虑的一种临床治疗方案。
Objective： To explore the clinical effect of Benazepril combined with Valsartan used for disease of diabetic nephropathy （DN）.Methods：213 eases of patients with DN were divided into group A,B and C.All groups were given routine therapy, group A were added to therapy of Benazepril,group B were added to therapy of Valsartan,group C were added to therapy of Benazepril combined with Valsartan. Results：After treatment of half year, compared with treatment before,the Cr, UAER and BUN in three groups all turned well in different degrees,But the group C was more significantly better（P〈0.05）.Conclusions：Benazepril combined with Valsartan used in patients with DN,was safe and effective,so it is one of the desirable drug treatment in clinical work.
出处
《中国医药导刊》
2011年第6期1036-1037,共2页
Chinese Journal of Medicinal Guide
关键词
贝那普利
缬沙坦
糖尿病肾病
Benazepril
Valsartan
Diabetic nephropathy （DN）
