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血浆脂联素、同型半胱氨酸与慢性心力衰竭关系的分析 被引量:3

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摘要 目的探讨脂联素(APN)、同型半胱氨酸(HCY)与慢性心力衰竭(CHF)的关系。方法 50例CHF患者,按照心功能NYHA分级分为3个亚组:CHFⅡ级组、Ⅲ级组、Ⅳ级组;选择同期健康体检者35例为对照组;所有观察对象均于住院次日清晨抽取空腹血测定APN、HCY。结果①CHF组患者血ANP、HCY浓度显著高于对照组,差异有统计学意义(P<0.05)。②CHF组患者随CHF分级的增加,血ANP、HCY水平逐步增高,差异有统计学意义(P<0.05)。③CHF组患者ANP与HCY呈正相关(r=0.583,P<0.05)。④CHF患者中ANP、HCY与左室射血分数值(LVEF)呈负相关(r=-0.029,P<0.05;r=-0.371,P<0.05)。结论 APN、HCY与CHF具有相关性,且为CHF预后的一个预测因子。
出处 《中华全科医学》 2011年第8期1244-1245,共2页 Chinese Journal of General Practice
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