摘要
目的:探讨血清甘胆酸(cholyglycine,CG)测定在妊娠肝内胆汁淤积症(intrahepatic cholestasis of pregnancy,ICP)中的临床意义。方法:对146例正常孕妇(对照组)和54例妊娠期ICP患者(ICP组)进行CG及其他肝功能指标的测定并分析。结果:ICP组血清CG、血清总胆汁酸(TBA)、丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、总胆红素(TBIL)测定结果均明显高于对照组,其差异具有统计学意义(P<0.01)。ICP组CG的升高阳性率高于其他肝功能指标。结论:血清CG是诊断及检测ICP的重要指标之一,可作为孕妇(特别是中晚期妊娠孕妇)的常规检测项目。
Objective：To investigative the significance of detection of serum cholyglycine（CG） in intrahepatic cholestasis of pregnancy（ICP）.Methods：Serum CG and other liver function indexes were detected and analyzed in 146 normal pregnant women and 54 cases of ICP.Results：In ICP group,the levels of serum CG,TBA,ALT,AST and TBIL all were obviously higher than those in the normal pregnant woman group,showing statistical difference between the two groups（P0.01）.The positive rate of CG increase in ICP group was higher than other liver function indexes.Conclusion：The serum CG is one of important indexes to diagnose and detect ICP,which can be used as the routine detection item of pregnant women,especially medium-term and late-term pregnant women.
出处
《现代医药卫生》
2011年第14期2104-2106,共3页
Journal of Modern Medicine & Health
关键词
妊娠期肝内胆汁淤积症
甘胆酸
总胆汁酸
Intrahepatic cholestasis of pregnancy（ICP）
cholyglycine（CG）
TBA
