期刊文献+

2型糖尿病患者血清CA199水平与血糖控制水平的观察 被引量:10

在线阅读 下载PDF
导出
摘要 目的探讨肿瘤标志物CA199在2型糖尿病患者及健康人群中的差异及糖化血红蛋白(HBA1c)对CA199的影响。方法用化学发光法检测100例2型糖尿病及100例健康体检者的血清CA199水平,其中2型糖尿病按HBA1c水平分为控制组(HBA1c小于7.5%)及未控制组(HBA1c大于7.5%)两组,比较各组CA199水平,计算HBA1c与CA199的相关性。结果 2型糖尿病患者CA199水平显著高于正常体检者。HBA1c未控制组CA199水平显著高于HBA1c控制组。HBA1c控制组与正常健康体检者CA199无显著差异。CA199水平高于正常的16例2型糖尿病患者在血糖控制1月后复查其中15例CA199水平下降至正常。结论 2型糖尿病患者CA199水平显著高于正常体检者,血糖未控制的高于血糖控制者,HBA1c控制组与正常健康体检者无显著差异。CA199与HBA1c呈显著正相关。2型糖尿病患者CA199水平升高与血糖控制不佳相关。
作者 张美纹
出处 《心脑血管病防治》 2011年第3期205-207,共3页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
  • 相关文献

参考文献5

二级参考文献79

  • 1李东野,常超,高铭枢,夏勇,陈清枝,陈静,王晓萍,吴兰芬.全心尖切面心肌背向散射积分参数评价心肌缺血[J].中国医学影像技术,2005,21(2):199-201. 被引量:5
  • 2徐婷,颜勤明,徐丽伟.2型糖尿病患者血清CA19-9浓度的变化及其与血糖的相关性[J].实用医学杂志,2007,23(5):676-677. 被引量:21
  • 3Locker GY, Hamilton S, Harris J, et al. ASCO 2006 update of recommendations for the use of tumor markers in gastroin testinal cancer[J]. J Clin Oncol, 2006, 24: 5313-5327.
  • 4Benhamou PY, Vuillez JP, Halimi S, et al. Influence of metabolic disturbances of diabetes mellitus on serum CA19-9 tumor marker[J]. Diabete Metab, 1991,17: 39-43.
  • 5Mohan V, Premalatha G , Pitchumoni CS. Pancreatic diseases and diabetes[M]. Textbook ofdiabetes. Eds: Pickup JC and Williams G. Third edition. USA:Black- well Publishing, 2003,28: 1-15.
  • 6廖二元 超楚生.内分泌学[M].北京:人民卫生出版社,2001.610-611.
  • 7Balen FG,Allen CM,Less WR,et al.Review ultrasound contrast agents[J].Clin Radiol,1994,49(1):77-82.
  • 8Matthews DR,Cull CA,Stratton IM,et al.UKPDS 26:Sulphonylurea failure in non-insulin-dependent diabetic patients over six years.UK Prospective Diabetes Study (UKPDS) Group[J].Diabet Med,1998,15(4):297-303.
  • 9Schecter SO,Teichholz LE,Klig V,et al.Ultrasonic tissue characterization:review of a noninvasive technique for assessing myocardial viability[J].Echocardiography,1996,13(4):415-430.
  • 10Alzaid A,Aideyam O,Nawaz S,et al.The size of pancreas in diabetes mellitus[J].Diabet Med,1993,10(8):759-763.

共引文献111

同被引文献67

  • 1徐婷,颜勤明,徐丽伟.2型糖尿病患者血清CA19-9浓度的变化及其与血糖的相关性[J].实用医学杂志,2007,23(5):676-677. 被引量:21
  • 2陈瑜,王磊,赵允文.血清CA19-9的酶免测定及临床应用[J].中国肿瘤临床,1997,24(6):408-410. 被引量:25
  • 3Aoki Y, Yanagisawa Y,Ohsa H,et al. Elevation of ser-um CA199 in parallel with HbAIc in a diabetic femalewith the Lewis (a + b) blood group[J], Diab Res ClinPract,1991,13(l-2):77-81.
  • 4Petit JM, Vaillant G, Olsson NO, et al. Elevated serumCA199 levels in poorly controlled diabetic patients[J].Gastroenterol Clin Biol, 1994 ,18(1) : 17-20.
  • 5Uygur - Bayramieli O, Dabak R, Orbay E, et al. Type 2 diabetes mellitus and CA199 levels [ J ]. World J Gastroenterol, 2007, 13 (40) :5357 -5359.
  • 6Petit JM, VaillantG, OlssonNO, et al. Elevated serum CA199 levels in poorly controlled diabetic patients [J]. Gastroenterol CliBiol, 1994,18( 1 ) :17 -20.
  • 7Park JK, Paik WH , Ryu JK, et al. Clinical significance and revisiting the meaning of CA19-9 blood level before and after the treatment of pancreatic ductal adenocarcino- ma: analysis of 1 ,rid6 patients from the pancreatic cancer cohort in a single institution [J]. PLoS One, 2013 ( 11 ) : e78977.
  • 8EI-Mesallamy HO, Hamdy NM, Zaghloul AS, et al. Clinical value of circulating lipocalins and insulin-like growth factor axis in pancreatic cancer diagnosis [ J ]. Pancreas, 2013 ( 1 ) : 149 - 154.
  • 9Yu H, Li R, Zhang L, et al. Serum CA19o9 level associ- ated with metabolic control and pancreatic beta cell func- tion in diabetic patients [ J]. Exp Diabetes Res, 2012 (12) : 745189.
  • 10Gul K, Nas S, Ozdemir D, Gumus M, et al. CA 19-9 level in patients with type 2 diabetes mellitus and its rela- tion to the metabolic control and microvascular complica- tions [J]. AmJMedSci, 2011(1) :28 -32.

引证文献10

二级引证文献46

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部