摘要
目的：观察苦参碱和参灵肝康胶囊联用抗肝纤维化疗效。方法：将90例慢性乙型肝炎肝纤维化活动度高的患者，随机分为治疗组和对照组。每组45例，两组均采用基本的保肝和苦参碱治疗，治疗组加服用参灵肝康胶囊。两组疗程为2个月，同时检查患者血清肝纤维化指标（HA．LN．Pcm）、肝功能并做肝脏彩超检测。结果：两组治疗后在疗效、肝功能、肝纤维化指标比较，差异有显著性意义（P〈0．01）。而两组患者在肝门静脉和脾厚方面比较差异无显著性意义（P〉0.05）。结果：苦参碱和参灵肝康胶囊联用抗肝纤维化疗效较对照组明显。
Objective Shen Ling observed matrine and liver capsule associated with anti-hepatic fibrosis effect.Methods 90 patients with high activities of liver fibrosis with chronic hepatitis B were randomly divided into treatment and control groups. 45 patients in each group, two groups have adopted the basic treatment of liver and matrine in the treatment group taking Shen Ling liver capsule. The treatment for 2 months, and also check the serum fibrosis markers （HA.LN.PC lU）, liver function and a liver ultrasound test.Results After treatment, in effect, liver function, liver fibrosis, the difference was significant （P 〈0.01）. The two groups were in the thick portal vein and spleen was no difference between areas was significant （P〉 0.05）.Conclusion Matrine and Shen Ling liver capsule associated with the efficacy of hepatic fibrosis compared with control group.
关键词
参灵肝康胶囊
治疗应用
苦参碱注射液
治疗应用
肝炎
乙型
慢性
肝纤维化
Shen Ling liver capsule / therapeutic use
matrine injection / therapeutic use
hepatitis B, chronic, liver fibrosis
