摘要
DNA甲基化是主要发生在CpG双核苷酸序列中胞嘧啶上的一种表面遗传修饰。它以S腺-苷甲硫氨酸为甲基供体,在DNA甲基酶的催化下,将甲基转移到胞嘧啶上,生成5-甲基胞嘧啶。DNA甲基化在植物的很多生命过程中具有重要的作用。本文就其作用机制、主要研究应用以及未来的前景进行综述,从而为DNA甲基化在植物遗传学中的研究提供理论参考。
DNA Methylation,most occurs in CpG dinucleotides is a kind of epigenetic modification.The most striking feature of DNA methylation patterns is the addition of a methyl group at the 5-position of cytosine in CpG dinucleotides by DNA methytransferase,which takes S-adenosylmethionine as methyl donor.DNA methylation has essential roles in many plant life processes.The characteristics of plant methylation,its regulating mechanisms,the effects on plants and the application of DNA methylation were reviewed in this paper,providing a theoretical references to DNA methylation research on plant genetics.
出处
《植物遗传资源学报》
CAS
CSCD
北大核心
2011年第3期425-430,共6页
Journal of Plant Genetic Resources
基金
南京中医药大学亚热带林业研究所基本科研业务费(No.RISF6807)
关键词
DNA甲基化
植物发育
调控
逆境胁迫
杂种优势
DNA methylation
Plant development
Regulation
Environmental stress
Wide-hybridization