摘要
目的比较右美托咪定和曲马多静脉注射用于治疗术后寒战的效果。方法90例全身麻醉后寒战级别为3～4级行腹部手术的患者，随机均分为三组：分别静注右美托咪定0．5“g／k（A组）、曲马多lH蜒／k（B组）和生理盐水（C组）。并按设定的时间间隔评估寒战级别和药物的不良反应。结果给药后5minA、B组寒战级别较C组降低（P〈O．05）。B组恶心呕吐发生率高于A、C两组（P〈O．05），A组的镇静评分高于B、C组。结论静注右美托咪定0．5μg／妇可以有效治疗术后寒战，恶心呕吐不良反应少。
Objective To evaluate the efficacy of dexmedetomidine in treatment of postoperative shivering. Methods Ninety ASA I or H patients scheduled for selective abdominal surgery under general anesthesia were enrolled in this study. Patients with shivering grade 3-4 were allocated to receive either dexlndetomidine 0. 5μg/kg tramadol 1 mg/kg, or saline IV. Shivering and side effects were observed at set time. Results Shivering grades for the first 5 min after treatment were lower in both the dexmetomidine groups and the trarnadol groups; however, the incidence of nausea and vomiting were higher in the tramadol groups. Sedation scores were significantly higher in the dexmetomidirne groups compared with the tramadol groups. Conclusion Intravenous administration of dexmdetomidine 0. 5 μg/kg is more suitable for the reduction of postoperative shivering than tramadol.
出处
《临床麻醉学杂志》
CAS
CSCD
北大核心
2011年第5期473-474,共2页
Journal of Clinical Anesthesiology
