摘要
目的探讨肿瘤标志物在癌性胸腔积液诊断中的价值。方法应用免疫放射分析法对108例癌性胸腔积液和90例良性胸腔积液的CYFRA21-1、CEA、NSE和CA153含量进行检测,并对结果进行比较分析。结果癌性胸腔积液中四种肿瘤标志物指标明显高于良性组(P<0.01),四项联检后的敏感性、特异性及准确性明显升高。结论肿瘤标志物CYFRA21-1、CEA、NSE和CA153四项联检在癌性胸腔积液的诊断中具有明确的意义。
Objective To investigate the diagnosis value of tumor markers（CYFRA21-1,CEA,NSE and CA153） in malignant pleural effusions.Methods 108 cases with malignant pleural effusions and 90 cases with benign pleural effusions were detected by radio immunoassay and ELISA,and then the results were compared.Results The four item of cancerous pleural effusion group were markedly higher than those of the benign ones（P0.01）.The sensitivity,specificity and accuracy rating of the combined detection of targets for diagnostician malignant pleural effusion were markedly higher.Conclusion The combined detection of CYFRA21-1,CEA,NSE and CA153 has specific value in the diagnosis for malignant pleural effusions.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
2011年第4期434-436,共3页
Cancer Research on Prevention and Treatment
关键词
肿瘤标志物
癌性胸腔积液
诊断
Tumor markers
Malignant pleural effusions
Diagnosis
