摘要
目的通过在线尿素清除率监测法研究血流量对尿素清除率K的影响。方法随机选择慢性。肾衰竭维持性血液透析的患者30例，观察比较血流量变化时的K值差异。第一组一次透析时将血流量先设定为200ml／min，2h后为250ml／min，其他参数不变，连续记录相对应的K值，分析血流量对K值的影响。第二组血流量先设定为250ml／min，2h后为280ml／min，余同前。第三组先后将3个血流量从小到大分别设置1h20min，余同前。结果单次透析过程中：血流量从200ml／min提高到250ml／min，或者从250ml／min提高到280ml／min时的K值有显著差异（t=5．570，P〈0．001；t=3．316，P〈0．01）。血流量从200ml／min提高到280ml／min，血流量与K值显著正相关，相关系数（r=0．573，P〈0．01），回归方程为：K=48．415＋0．546×血流量。结论单次透析过程中，透析效率与血流量成正比。
Objective To assess the effect of blood flow（BF） on the rate of urea removal（K） by measuring blood flow of access and K of hemodialysis patients. Methods BF of access and K during one hemodialysis session were observed. The relationship between BF of access and K was analyzed. Results As BF was increased from 200 ml/min to 250 ml/min or from 250 ml/min to 280 ml/min,K was increased significantly（t = 5. 570, P〈0. 001 ; t = 3. 316, P〈0. 01 respective/y）. As BF was increased from 200 ml/min to 280 ml/min progressively, there was a significantly positive correlation between BF and K （r = 0. 573, P〈0. 001 ）, and the regression equation was K = 48. 415 ＋ 0. 546 x BF. Conclusions The rate of urea removal was positively correlated with BF of access during one hemodialysis session.
出处
《临床肾脏病杂志》
2011年第3期117-119,共3页
Journal Of Clinical Nephrology
关键词
尿素
肾衰竭
肾透析
Urea
Kidney Failure
Renal Dialysis
