摘要
血管性认知功能损害（vascular cognitive impair-ment,VCI）是指所有由血管性因素导致的从轻度认知障碍到痴呆的一大类综合征。Wentzel提出标准诊断血管性痴呆（vascular dementia,VaD）和血管性无痴呆型认知损害（cognitive impairment no dementia,CIND）。按病灶部位分类可分为皮层型、皮层下型和多发梗死型,其中皮层下型又可以分为皮层下关键部位梗死型、皮层下小血管型。
Objective To compare the characteristics of executive function impairment in single thalamus or basal ganglia stroke patients.Methods Study included 63 patients with single thalamus or basal ganglia stroke（4 groups： left or right thalamus stroke,left or right basal ganglia stroke） and 34 healthy controls（control group）.Executive functions including trail making test（TMT）,Stroop color words test（SCWT）,similarity test（ST） and symbol digit modalities test（SDMT）were evaluated in all people including 4 groups of single thalamus or basal ganglia stroke patients and control group.Comparison was made between single thalamus or basal ganglia stroke patients and control group.Results Information processing speed,the abilities of reasoning and transformation（set-shifting）,the interference inhibition ability and abstraction ability,working memory and attention were extensively impaired after thalamus or basal ganglia stroke. The decrease of score in ST closely was correlated with left and right thalamus stroke,which indicated that abstraction ability was obviously impaired after thalamus stroke.Among 4 groups（left or right thalamus stroke,left or right basal ganglia stroke）,patients with left thalamus stroke performed the worst in SDMT.The interference inhibition ability of patients in right basal ganglia stroke group was the best than that in left/right thalamus and left basal ganglia stroke groups.The patients in left basal ganglia stroke group performed obviously better than those in other 3 groups in speed and accuracy of information processing,reasoning and transformation（set-shifting）.Conclusions Executive function was extensively impaired after thalamus or basal ganglia stroke,especially the impairment was more severe in patients with left thalamus stroke.
出处
《心脑血管病防治》
2011年第2期96-98,I0001,共4页
CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
