期刊文献+

骨髓增生活跃的特殊类型全血细胞减少患者应用糖皮质激素疗效分析 被引量:2

Clinical Effect of Glucocorticoid in Special Pancytopenia and Bone Marrow Hyperplasia
在线阅读 下载PDF
导出
摘要 目的观察对骨髓增生活跃、网织红细胞计数>1%、排除白血病等可引起全血细胞减少的疾病,及无足够证据诊断免疫相关性全血细胞减少和溶血性贫血的临床难于诊治的全血细胞减少患者给予应用糖皮质激素的早期疗效。方法回顾分析12例符合上述条件患者应用糖皮质激素治疗的效果。结果患者外周血白细胞、中性粒细胞绝对值、血红蛋白浓度有明显升高(P<0.05),出血等症状改善。结论对于符合上述条件患者,早期应用糖皮质激素治疗有明显效果。 Objective To evaluate the pristine effects of glucocorticoid in the treatment of pancytopenia patients,who were difficult to be diagnosed because they had bone marrow hyperplasia,reticulocyte counts no less than 1%,eliminations of leukemia and other diseases which can cause pancytopenia,not enough evidence of immunorelated pancytopenia. Methods 12 cases of such patients were analyzed retrospectively. Results The total counts of peripheral blood leucocyte,neutrophile granulocyte,haematoglobin of these patients were significantly increased after treatment(P〈0.05),and the symptoms,such as bleeding and hypodynamia,were relieved. Conclusion It might have good effect that glucocorticoid application in the early stages for the patients who were meeting the above conditions.
出处 《黑龙江医学》 2011年第2期81-83,86,共4页 Heilongjiang Medical Journal
基金 国家中医药管理局中医药科学技术研究专项课题06-07LP15"沙利度胺逆转三氧化二砷耐药机制及临床疗效评价"资助
关键词 全血细胞减少 糖皮质激素 网织红细胞 Pancytopenia Glucocorticoid Reticulocyte counts
  • 相关文献

参考文献8

二级参考文献27

共引文献7

同被引文献14

  • 1Rollison D E, Howlader N, Smith M T, et al. Epidemiology of myelodysplastic syndromes and chronic myeloproliferative disorders in the United States, 2001 -2004, using data from the NAACCR and SEER programs [ J ]. Blood,2008,112 ( 1 ): 45 - 52.
  • 2Swerdlow S H, Campo E, Harris N L, et al. WHO classifica- tion of tumours of haematopoietic and lymphoid tissues [ M ]. 4th Edition. Lyon: IARC Press,2008:87 - 103.
  • 3Valent P, Orazi A, Btische G, et al. Standards and impact of hematopathology in myelodysplastic syndromes ( MDS ) [ J ]. Oncotarget, 2010, 1(7): 483-496.
  • 4Das R, Hayer I, Dey P, et al. Comparative study of myelo- dysplastic syndromes and normal bone marrow biopsies with conventional staining and immunocytochemistry[ J]. Analyti- cal and Quantitative Cytology and Histology/The Internation- al Academy of Cytology and American Society of Cytology, 2005,27(3) : 152 - 156.
  • 5陈文杰,陈辉树造血系统疾病临床病理学[M].北京:北京医科大学中国协和医科大学联合出版社,1977:3-4.
  • 6刘芳.骨髓活检在诊断再生障碍性贫血中的作用[J].中国农村卫生,2014:399-400.
  • 7孔荣,骨髓活检及涂片联合染色体同步观察在全血细胞减少病人的临床价值探讨[j].l中国中医药科技,2014(z2):84-85.
  • 8于桂芬,闫冬梅,秦继宝.全血细胞减少138例分析[J].中国误诊学杂志,2008,8(3):641-642. 被引量:1
  • 9岳兰竹,邵宗鸿.多指标综合诊断骨髓增生异常综合征[J].中国实用内科杂志,2010,30(5):395-397. 被引量:6
  • 10何广胜,吴德沛,孙爱宁,梁建英,刘丹丹,陈子兴,薛永权,阮长耿.WHO 2008年骨髓增生异常综合征诊断与分型修订解读[J].中国实用内科杂志,2010,30(5):416-421. 被引量:43

引证文献2

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部