摘要
目的探讨子宫动脉灌注化疗栓塞联合清宫术治疗胎盘植入的可行性和安全性。方法 2006年1月至2010年6月在复旦大学附属妇产科医院就诊的23例胎盘植入患者行子宫动脉化疗栓塞术,经双侧子宫动脉灌注MTX各100 mg,庆大霉素8万u,再以明胶海绵栓塞,术后3～10 d行清宫术。结果子宫动脉化疗栓塞术手术成功率100%。清宫术时出血45～190 ml,平均78.5 ml。无严重并发症发生。结论子宫动脉化疗栓塞配合清宫术可明显降低胎盘植入子宫切除和丧失生育能力的风险,是治疗胎盘植入安全可行的方法。
Objective To discuss the efficacy and safety of uterine artery chemoembolization combined with curettage of uterus in treating placenta accreta.Methods During the period of Jan.2006-June 2010,uterine artery chemoembolization was performed in 23 patients with placenta accreta in authors＇ hospital.Via bilateral uterine arteries 100mg MTX and 80 000 u Gentamycin were infused separately,which was followed by embolization of bilateral uterine arteries with Gelfoam.Curettage of uterus was carried out within 3-10 days after the procedure.Results The technical success rate of bilateral uterine artery chemoembolization was 100%.The blood loss was 45-190 milliliters（mean 78.5 ml） during the procedure of curettage of uterus.No serious complications occurred.Conclusion The uterine artery chemoembolization combined with curettage of uterus is an effective and safe treatment for placenta accreta.This technique can greatly avoid unnecessary uterectomy and,thus,preserve the fertility of the female patients.（J Intervent Radiol,2010,19： 947-950）
出处
《介入放射学杂志》
CSCD
北大核心
2010年第12期947-950,共4页
Journal of Interventional Radiology
关键词
胎盘植入
子宫动脉化疗栓塞
清宫术
甲氨蝶呤
placenta accreta
uterine artery chemoembolization
curettage of uteru
methotrexate
