摘要
本文对65例肾活检中的9例膜增殖性肾小球肾炎(MPGN)超微结构进行了分析,其特点为MPGN-Ⅰ型以内皮下电子致密沉积物为主,MPGN-Ⅱ型以基底膜致密层电子致密沉积物为主,同时在两型中伴有肾小球基底膜不规则增厚,系膜细胞、基质的增多并插入基底膜和内皮细胞之间。结果表明,膜增殖性肾小球肾炎的超微结构在病理学分型、诊断和鉴别诊断中具有重要意义。
9 cases of membranoproliferative glomerulonephritis (MPGN) of 65 renal biopsy specimens were analysed by electron microscopy.It was found ultras-tructurally that MPGN-Ⅰ type is characterized mainly by electron-dense deposits in subendothelial locations while MPGN-Ⅱ type by electron-dense deposits in densa lamina of GBM.Moreover,these two types are usually associated with the thickening of GBM,increase of mesangical cells and matrix,extension and interposition of mesangium between the basement membranes and endothelial cells.The above results demonstrate that the ultrastructure of MPGN is of important significance in pathological and differential diagnosis.
出处
《同济医科大学学报》
CSCD
北大核心
1990年第2期92-94,142,共3页
Acta Universitatis Medicinae Tongji
关键词
肾小球肾炎
超微结构
病理
诊断
ultrastructure
membranoproliferative glomerulonephritis
