摘要
非小细胞肺癌是一种常见的恶性肿瘤，化学治疗的疗效似已达到平台，而分子靶向治疗以其符合生理、低毒和理论上高效的特点，越来越成为晚期非小细胞肺癌治疗的热点。文章就分子靶向治疗的作用靶点包括表皮生长因子受体、血管内皮因子受体，还有最近发现的EML4-ALK等进行综述，以展示分子靶向药物对于晚期非小细胞肺癌治疗的良好前景。
Non-small cell lung cancer is a common malignant tumor, the efficacy of chemotherapy has reached a plateau, and the molecular targeted therapy characterized by low toxicity and high efficiency has increasingly become a focus of treatment of advanced non-small cell lung cancer. This paper reviews the targets of molecular targeted therapy, including epidermal growth factor receptor, vascular endothelial growth factor receptor, as well as EML4- ALK recently discovered, etc. to show the good prospects of molecular targeted drugs for the treatment of advanced non small cell lung cancer.
出处
《国际呼吸杂志》
2011年第8期637-640,共4页
International Journal of Respiration
关键词
非小细胞肺癌
分子靶向治疗
表皮生长因子受体
血管内皮因子生长受体
Non-small cell lung cancer
Molecular targeted therapy
Epidermal growth factor receptor
Vascular endothelial growth factor receptor
