摘要
目的：研究肝动脉灌注LAK细胞／白介素Ⅱ，联合化疗栓塞治疗原发性肝癌的价值。方法：肝动脉灌注LAK细胞／白介素Ⅱ，联合化疗栓塞治疗原发性肝癌17例（观察组），与单纯肝动脉化疗栓塞治疗原发性肝癌17例（对照组）。对两组病例的疗效及生存期进行对比观察。结果：观察组总有效率与1年生存率均较对照组显著提高（P＜0.01）;观察组2年生存率也明显高于对照组（P＜0.05）。结论：肝动脉灌注的LAK细胞/白介素Ⅱ与某些化疗药物具有协同杀伤肿瘤细胞的作用，LAK细胞／白介素Ⅱ又可作用于机体免疫系统，显著改善或重建机体免疫功能，克服化疗栓塞使患者免疫力更加低下的副作用，从而提高疗效，延长患者生存期。肝动脉灌注LAK细胞／白介素Ⅱ联合化疗栓塞，是原发性肝癌很有价值的治疗方法。
Objective: To evaluate the effect of perfusing LAK cells/interleukin Ⅱ into hepatic artery combinde with convention al chemeeinhalization in the therapy of primary linver cancer Methode: l7 cases of primmp liver cancer accepted Perfusing LAK cells/in terleukin Ⅱ into hepatic artery combined with chemoedriizaion as observing group. Ⅱ cases of primp liver cancer accepted only chemoemboization as control group. The therapeutic effects and survival rates of the two groups were compared. Results: The total efficiency and l year survival the of observing group un apparnily higher as commpd to those of control group (P < 0. 0l ); the 2 years survival rate of obeerving group were also apparenily highe than control gnup (P < 0. 05). conclndons: cowhined with some chemotherapy mwhcines, the LAK cells/interleukin nperfused into hepatic artery Possesses funtion to kill tumor cells. perfuson of LAK cells/interleukin Ⅱ into hepaic artery coinbined with conventional chetnoembolization is a very valuabe method for beatmnt of Primary liver cancer.
出处
《放射学实践》
1999年第3期178-179,共2页
Radiologic Practice
