摘要
目的 为骺板组织工程寻找生物相容性良好的支架材料。方法 将体外培养的第三代骺板软骨细胞与可降解多孔丝素材料复合。应用扫描电镜、激光共聚焦显微镜、MTT等方法，对骺板软骨细胞与可降解多孔丝素材料的生物相容性进行观察。结果 骺板软骨细胞在可降解多孔丝素材料上生长良好，随着培养时间的延长，骺板软骨细胞逐渐增多。结论 可降解多孔丝素材料具有良好的生物相容性，可以作为骺板组织工程理想的支架材料。
Objective To assessfind the biocompatibility of scaffold SF for epiphyseal plate tissue engineering. Methods To culture the epiphyseal plate chondrocyte on scaffold SF. We studied biological characteristics of the cells by applying the ways of scanning electron- microscope, laser scan confocal microscope and MTT test. Results The epiphyseal plate chondrocyte grew well on scaffold SF. Conclusions The scaffold SF have good biocompatibility and can be used as ideal scaffold in epiphyseal plate tissue engineering.
出处
《中华小儿外科杂志》
CSCD
北大核心
2011年第3期214-217,共4页
Chinese Journal of Pediatric Surgery
关键词
组织工程
软骨细胞
生物相容性材料
Tissue engineering
Chondroeytes
Biocompatible materials
